Endoscopy 2017; 49(02): 186-190
DOI: 10.1055/s-0042-118450
Innovations and brief communications
© Georg Thieme Verlag KG Stuttgart · New York

The adenoma miss rate of blue-laser imaging vs. white-light imaging during colonoscopy: a randomized tandem trial

Ryo Shimoda
1   Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan
,
Yasuhisa Sakata
1   Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan
,
Takehiro Fujise
1   Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan
,
Kohei Yamanouchi
1   Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan
,
Nanae Tsuruoka
1   Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan
,
Megumi Hara
2   Department of Preventive Medicine, Saga Medical School, Japan
,
Atsushi Nakayama
1   Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan
,
Daisuke Yamaguchi
1   Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan
,
Takashi Akutagawa
1   Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan
,
Kazuma Fujimoto
1   Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan
,
Ryuichi Iwakiri
1   Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan
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Publikationsverlauf

submitted 16. März 2016

accepted after revision 08. September 2016

Publikationsdatum:
14. November 2016 (online)

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Abstract

Background and study aims The aim of the present study was to determine whether blue-laser imaging (BLI) reduced the miss rate of colon adenomatous lesions compared with conventional white-light imaging (WLI).

Patients and methods This was a prospective randomized study of patients undergoing screening and/or surveillance colonoscopy at Saga Medical School, Japan. A total of 127 patients were randomized to tandem colonoscopy with BLI followed by WLI (BLI-WLI group) or WLI followed by WLI (WLI-WLI group). The main outcome measure was the adenoma miss rate.

Results The proportion of patients with adenomatous lesions was 62.5 % (40 /64) in the BLI-WLI group and 63.5 % (40 /63) in the WLI-WLI group. The total number of adenomatous lesions detected in the first inspection of the BLI-WLI and WLI-WLI groups was 179 and 108, respectively, compared with 182 and 120 in the second inspection, respectively. The miss rate in the BLI-WLI group was (1.6 %), which was significantly less than that in the WLI-WLI group (10.0 %, P = 0.001).

Conclusions Colonoscopy using BLI resulted in a lower colon adenoma miss rate than WLI.

Trial registration UMIN 000015677.