Int J Angiol 2023; 32(04): 262-268
DOI: 10.1055/s-0042-1743409
Case Report

COVID-19-Associated Portal Vein Thrombosis Post-Cholecystitis

Sara Guevara*
1   Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York
2   Department of Family Medicine, Glen Cove Hospital, Glen Cove, New York
,
Santiago J. Miyara*
3   Feinstein Institutes for Medical Research, Manhasset, New York, USA
4   Elmezzi Graduate School of Molecular Medicine, Manhasset, New York
,
Judith Aronsohn*
1   Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York
5   Department of Anesthesiology, North Shore University Hospital, Manhasset, New York
,
Joseph T. Homsi
6   Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
,
Alexia McCann-Molmenti
7   Department of Surgery, North Shore University Hospital, Manhasset, New York
,
James M. Mumford
1   Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York
2   Department of Family Medicine, Glen Cove Hospital, Glen Cove, New York
,
Barbara Keber
1   Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York
2   Department of Family Medicine, Glen Cove Hospital, Glen Cove, New York
,
Linda Shore-Lesserson
1   Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York
5   Department of Anesthesiology, North Shore University Hospital, Manhasset, New York
,
Luis Morales
7   Department of Surgery, North Shore University Hospital, Manhasset, New York
,
Christine N. Metz
1   Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York
3   Feinstein Institutes for Medical Research, Manhasset, New York, USA
4   Elmezzi Graduate School of Molecular Medicine, Manhasset, New York
,
Young Min Cho
8   Department of Internal Medicine, Northeast Georgia Medical Center, Gainesville, Georgia
,
Christine L. Sardo Molmenti
9   Department of Occupational Medicine, Epidemiology and Prevention, Northwell Health, Great Neck, New York
,
Rodrigo Loto
10   Department of Radiology, Delta Sanatorium, Rosario, Santa Fe, ARG
,
Martin M. Pesce
10   Department of Radiology, Delta Sanatorium, Rosario, Santa Fe, ARG
,
Stefanos Zafeiropoulos
3   Feinstein Institutes for Medical Research, Manhasset, New York, USA
4   Elmezzi Graduate School of Molecular Medicine, Manhasset, New York
,
Dimitrios Giannis
3   Feinstein Institutes for Medical Research, Manhasset, New York, USA
,
Derek O. Pipolo
7   Department of Surgery, North Shore University Hospital, Manhasset, New York
,
Francky Jacque
7   Department of Surgery, North Shore University Hospital, Manhasset, New York
,
Lisandro Montorfano
7   Department of Surgery, North Shore University Hospital, Manhasset, New York
,
Koichiro Shinozaki
1   Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York
11   Department of Emergency Medicine, North Shore University Hospital, Manhasset, New York
,
Muhammad Shoaib
1   Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York
3   Feinstein Institutes for Medical Research, Manhasset, New York, USA
,
Rishabh C. Choudhary
3   Feinstein Institutes for Medical Research, Manhasset, New York, USA
11   Department of Emergency Medicine, North Shore University Hospital, Manhasset, New York
,
Mitsuaki Nishikimi
3   Feinstein Institutes for Medical Research, Manhasset, New York, USA
11   Department of Emergency Medicine, North Shore University Hospital, Manhasset, New York
,
Ryosuke Takegawa
3   Feinstein Institutes for Medical Research, Manhasset, New York, USA
11   Department of Emergency Medicine, North Shore University Hospital, Manhasset, New York
,
Yusuke Endo
3   Feinstein Institutes for Medical Research, Manhasset, New York, USA
11   Department of Emergency Medicine, North Shore University Hospital, Manhasset, New York
,
Kei Hayashida
3   Feinstein Institutes for Medical Research, Manhasset, New York, USA
11   Department of Emergency Medicine, North Shore University Hospital, Manhasset, New York
,
Fermin M. Fontan
12   Department of Surgery, Memorial Medical Center, Las Cruces, New Mexico
,
Lance B. Becker
1   Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York
3   Feinstein Institutes for Medical Research, Manhasset, New York, USA
4   Elmezzi Graduate School of Molecular Medicine, Manhasset, New York
11   Department of Emergency Medicine, North Shore University Hospital, Manhasset, New York
,
Ernesto P. Molmenti
1   Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York
3   Feinstein Institutes for Medical Research, Manhasset, New York, USA
7   Department of Surgery, North Shore University Hospital, Manhasset, New York
› Author Affiliations
Funding None.
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Abstract

This case study describes a 45-year-old Caucasian male with a past medical history of obesity, hypertension, and non-insulin-dependent diabetes mellitus, who in the setting of coronavirus disease 2019 (COVID-19) pneumonia, developed portal vein thrombosis (PVT) presenting as an acute abdomen after hospital discharge from a cholecystitis episode. PVT is a very infrequent thromboembolic condition, classically occurring in patients with systemic conditions such as cirrhosis, malignancy, pancreatitis, diverticulitis, autoimmunity, and thrombophilia. PVT can cause serious complications, such as intestinal infarction, or even death, if not promptly treated. Due to the limited number of reports in the literature describing PVT in the COVID-19 setting, its prevalence, natural history, mechanism, and precise clinical features remain unknown. Therefore, clinical suspicion should be high for PVT, in any COVID-19 patient who presents with abdominal pain or associated signs and symptoms. To the best of our knowledge, this is the first report of COVID-19-associated PVT causing extensive thrombosis in the portal vein and its right branch, occurring in the setting of early-stage cirrhosis after a preceding episode of cholecystitis.

* Authors had equal contribution.




Publication History

Article published online:
24 May 2022

© 2022. International College of Angiology. This article is published by Thieme.

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