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CC BY-NC-ND 4.0 · Arch Plast Surg 2022; 49(02): 141-149
DOI: 10.1055/s-0042-1744422
Breast/Trunk
Review Article

Comprehensive Evaluation of the Current Knowledge on Breast Implant Associated-Anaplastic Large Cell Lymphoma

Hyokyung Yoo
1   Department of Plastic and Reconstructive Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
,
Ji-Ung Park
2   Department of Plastic and Reconstructive Surgery, Seoul National University Boramae Hospital, Seoul National University College of Medicine, Seoul, Korea
,
Hak Chang
1   Department of Plastic and Reconstructive Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
› Institutsangaben Funding None.
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Abstract

Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a recently spotlighted T-cell origin non-Hodgkin's lymphoma with an increasing incidence of over 800 cases and 33 deaths reported worldwide. Development of BIA-ALCL is likely a complex process involving many factors, such as the textured implant surface, bacterial biofilm growth, immune response, and patient genetics. As the incidence of BIA-ALCL is expected to increase, it is important for all surgeons and physicians to be aware of this disease entity and acquire thorough knowledge of current evidence-based guidelines and recommendations. Early detection, accurate diagnosis, and appropriate treatment are the foundations of current care.

Keywords

BIA-ALCL - breast implants - biofilm - immunity - genetics

Author Contributions

Conceptualization: H.C. Data curation: J.U.P. Methodology: all authors. Project administration: all authors. Visualization: J.U.P. Writing—original draft: H.Y. Writing—review and editing: H.Y.




Publikationsverlauf

Artikel online veröffentlicht:
06. April 2022

© 2022. The Korean Society of Plastic and Reconstructive Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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