Genicular Artery Embolization for Primary Knee Osteoarthritis

Ravi Tyagi; S. Samaduddin Ahmed; Yilun Koethe; Aleksandr Raskind; Osman Ahmed

doi:10.1055/s-0042-1745798

Seminars in Interventional Radiology, Table of Contents

Semin intervent Radiol 2022; 39(02): 125-129
DOI: 10.1055/s-0042-1745798

Review Article

Genicular Artery Embolization for Primary Knee Osteoarthritis

Authors

Ravi Tyagi

¹University of Illinois College of Medicine at Chicago, Chicago, Illinois
S. Samaduddin Ahmed

²Chicago College of Osteopathic Medicine, Midwestern University, Downers Grove, Illinois
Yilun Koethe

³Dotter Department of Interventional Radiology, Oregon Health and Science University, Portland, Oregon
Aleksandr Raskind

²Chicago College of Osteopathic Medicine, Midwestern University, Downers Grove, Illinois
Osman Ahmed

⁴Section of Interventional Radiology, Department of Radiology, University of Chicago, Chicago, Illinois

Abstract

Genicular artery embolization (GAE) is a novel treatment for knee osteoarthritis (OA) with increasing interest and utilization worldwide. The genicular arteries are selectively embolized using microspheres with subsequent cessation of abnormal synovial hyperemia, a process believed to arrest the inflammatory changes and pain associated with OA. Current data indicate that GAE offers sustained, 6-month improvement in Western Ontario and McMaster Universities Osteoarthritis index (WOMAC) and visual analog scale scores in 80 to 85% of patients with mild to moderate OA. As GAE gains traction, future studies are needed to establish its safety and efficacy relative to placebo and other standard-of-care therapies while also characterizing populations for which it is most effective.

Keywords

GAE - genicular artery embolization - osteoarthritis - embolization - WOMAC - WORMS - VAS - interventional radiology

Full Text

References

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