CC BY-NC-ND 4.0 · Laryngorhinootologie 2022; 101(S 02): S330
DOI: 10.1055/s-0042-1747027
Poster
Rhinology: Mucous membrane

Morphological changes of the nasal mucosa in patients with sarcoidosis

Evangelia Fouka
1   Papanikolaou-Klinikum, Pulmonary Department of Aristotle University of Thessaloniki Thessaloniki Greece
,
Pavlos Pavlidis
2   Papanikolaou-Klinikum, Thessaloniki, HNO Thessaloniki Greece
,
GregorAlexander Schittek
3   Medical University of Graz, Division of General Anaesthesiology, Emergency- and Intensive Care Medicine, Graz Austria
,
Despoina Papakosta
4   Papanikolaou-Klinikum, Pulmonary Department of Aristotle University of Thessaloniki, Thessaloniki, Greece Thessaloniki Greece
,
Haralampos Gouveris
5   Universitätsklinikum Mainz, HNO-Klinik Mainz
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Introduction Sarcoidosis is a chronic non-caseating granulomatous disease of unknown etiology with a predilection for the respiratory tract. Sinonasal involvement is a rare manifestation. So far, little is known about the changes in the microvascular network of the nasal mucosa. We retrospectively analyzed 15 cases of biopsy-proven sinonasal sarcoidosis. The patients’ nasal mucosa was examined with a contact endoscope. Their olfaction was also examined with Schniffin’ Sticks. The patients’ findings were compared to those of 15 healthy subjects.

Results The nasal microvascular network was disrupted in the majority of the patients. In one patient no vesicles could be detected. We noticed hyposmia in four patients (1 male, 3 females) and anosmia in only one patient.

Conclusions Mucosal changes in sinonasal sarcoidosis is of utmost interest. Clinical course can be complicated due to relapse, systemic immunosuppressive treatment and repeated sinus surgery.



Publication History

Article published online:
24 May 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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