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DOI: 10.1055/s-0042-1749123
Primary Breast Tuberculosis Mastitis Manifested as Nonhealing Abscess
Funding This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.Abstract
Primary breast tuberculosis (TB) is a rare extrapulmonary TB mainly affecting young women of childbearing age from endemic countries. Its incidence is increasing in immunocompromised and HIV-infected people and with the emergence of drug-resistant strains of Mycobacterium tuberculosis (MTB). There are no specific clinical signs suggestive of this disease, it often presents as a hard mass or breast abscess. There is an overlap of features with other inflammatory, infectious, benign lesions, fat necrosis and malignant neoplasms of the breast. The detection of MTB remains the gold standard for diagnosis. Several other diagnostic modalities are used, with varying lack of sensitivity and specificity, and with a range of false negatives. A quarter of cases were treated solely on the basis of clinical, imaging or histological suspicion, without confirmation of the diagnosis. Therefore, we report the case of a young Vietnamese woman, presented for a nonhealing breast abscess, and diagnosed with breast TB based on the patient's ethnicity, histological findings, lack of clinical response to conventional antibiotic therapy, and a good clinical response to anti-TB treatment.
Keywords
breast abscess - mycobacterium tuberculosis - extrapulmonary tuberculosis - breast tuberculosis - case reportPublication History
Received: 14 January 2022
Accepted: 07 April 2022
Article published online:
14 June 2022
© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
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References
- 1 Sinha R. Rahul. Breast tuberculosis. Indian J Tuberc 2019; 66 (01) 6-11
- 2 Baykan AH, Sayiner HS, Inan I, Aydin E, Erturk SM. Primary breast tuberculosis: imaging findings of a rare disease. Insights Imaging 2021; 12 (01) 19
- 3 Quaglio G, Pizzol D, Isaakidis P. et al. Breast tuberculosis in women: a systematic review. Am J Trop Med Hyg 2019; 101 (01) 12-21
- 4 Jørstad MD, Dyrhol-Riise AM, Aßmus J, Marijani M, Sviland L, Mustafa T. Evaluation of treatment response in extrapulmonary tuberculosis in a low-resource setting. BMC Infect Dis 2019; 19 (01) 426
- 5 McGuire E, Carey L, Tiberi S. et al. Breast tuberculosis in East London: a 13-year retrospective observational study. Breast J 2020; 26 (02) 235-239