Use of Continuous EEG Monitoring and Short-Term Outcomes in Critically Ill Children

Xiuhua Liang Bozarth; Pin-Yi Ko; Hao Bao; Nicholas S. Abend; R Scott Watson; Pingping Qu; Leslie A. Dervan; Lindsey A. Morgan; Mark Wainwright; John K. McGuire; Edward Novotny

doi:10.1055/s-0042-1749433

Journal of Pediatric Intensive Care, Table of Contents

J Pediatr Intensive Care
DOI: 10.1055/s-0042-1749433

Original Article

Use of Continuous EEG Monitoring and Short-Term Outcomes in Critically Ill Children

Xiuhua Liang Bozarth

¹Division of Pediatric Neurology, Department of Neurology, University of Washington, Seattle, Washington, United States

,

Pin-Yi Ko

¹Division of Pediatric Neurology, Department of Neurology, University of Washington, Seattle, Washington, United States

,

Hao Bao

²Biostatistics, Epidemiology, Econometrics and Programming Core, Seattle Children's Research Institute, Washington, United States

,

Nicholas S. Abend

³Division of Neurology, Departments of Neurology and Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, United States

,

R Scott Watson

⁴Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington, Seattle, Washington, United States

⁵Center for Child Health, Behavior, and Development, Seattle Children's Research Institute, Seattle, Washington, United States

,

Pingping Qu

²Biostatistics, Epidemiology, Econometrics and Programming Core, Seattle Children's Research Institute, Washington, United States

,

Leslie A. Dervan

⁴Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington, Seattle, Washington, United States

,

Lindsey A. Morgan

¹Division of Pediatric Neurology, Department of Neurology, University of Washington, Seattle, Washington, United States

,

Mark Wainwright

¹Division of Pediatric Neurology, Department of Neurology, University of Washington, Seattle, Washington, United States

,

John K. McGuire

⁴Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington, Seattle, Washington, United States

,

Edward Novotny

¹Division of Pediatric Neurology, Department of Neurology, University of Washington, Seattle, Washington, United States

⁶Center for Integrative Brain Research, Seattle Children's Research Institute, Washington, United States

› Author Affiliations

Abstract

This study aimed to compare short-term outcomes at pediatric intensive care unit (PICU) discharge in critically ill children with and without continuous electroencephalography (cEEG) monitoring. We retrospectively compared 234 patients who underwent cEEG with 2294 patients without cEEG. Propensity score matching was used to compare patients with seizures and status epilepticus between cEEG and historical cohorts. The EEG cohort had higher in-hospital mortality, worse Pediatric Cerebral Performance Category (PCPC) scores, and greater PCPC decline at discharge. In patients with status epilepticus, the PCPC decline was higher in the cEEG cohort. PCPC decline at PICU discharge was associated with cEEG monitoring in patients with status epilepticus.

Keywords

EEG monitoring - outcomes - critically ill children

Full Text

References

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