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J Pediatr Intensive Care
DOI: 10.1055/s-0042-1749433
Original Article

Use of Continuous EEG Monitoring and Short-Term Outcomes in Critically Ill Children

Xiuhua Liang Bozarth
1   Division of Pediatric Neurology, Department of Neurology, University of Washington, Seattle, Washington, United States
,
Pin-Yi Ko
1   Division of Pediatric Neurology, Department of Neurology, University of Washington, Seattle, Washington, United States
,
Hao Bao
2   Biostatistics, Epidemiology, Econometrics and Programming Core, Seattle Children's Research Institute, Washington, United States
,
Nicholas S. Abend
3   Division of Neurology, Departments of Neurology and Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, United States
,
R Scott Watson
4   Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington, Seattle, Washington, United States
5   Center for Child Health, Behavior, and Development, Seattle Children's Research Institute, Seattle, Washington, United States
,
Pingping Qu
2   Biostatistics, Epidemiology, Econometrics and Programming Core, Seattle Children's Research Institute, Washington, United States
,
Leslie A. Dervan
4   Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington, Seattle, Washington, United States
,
Lindsey A. Morgan
1   Division of Pediatric Neurology, Department of Neurology, University of Washington, Seattle, Washington, United States
,
Mark Wainwright
1   Division of Pediatric Neurology, Department of Neurology, University of Washington, Seattle, Washington, United States
,
John K. McGuire
4   Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington, Seattle, Washington, United States
,
Edward Novotny
1   Division of Pediatric Neurology, Department of Neurology, University of Washington, Seattle, Washington, United States
6   Center for Integrative Brain Research, Seattle Children's Research Institute, Washington, United States
› Author Affiliations Funding None.
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Abstract

This study aimed to compare short-term outcomes at pediatric intensive care unit (PICU) discharge in critically ill children with and without continuous electroencephalography (cEEG) monitoring. We retrospectively compared 234 patients who underwent cEEG with 2294 patients without cEEG. Propensity score matching was used to compare patients with seizures and status epilepticus between cEEG and historical cohorts. The EEG cohort had higher in-hospital mortality, worse Pediatric Cerebral Performance Category (PCPC) scores, and greater PCPC decline at discharge. In patients with status epilepticus, the PCPC decline was higher in the cEEG cohort. PCPC decline at PICU discharge was associated with cEEG monitoring in patients with status epilepticus.

Keywords

EEG monitoring - outcomes - critically ill children


Publication History

Received: 25 February 2020

Accepted: 04 April 2022

Article published online:
12 July 2022

© 2022. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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