Abstract
Since 2012, Xu and Zhou have reported the isolation of a series of gymnotheligans, a large group of novel tetrahydrofuran-containing lignan natural products. In the past decade, considerable achievements in the total syntheses of these lignans have been achieved based on a plausible biogenetic pathway proposed by our group in 2014. In this account, we summarize these remarkable synthetic works of the past ten years.
1 Introduction
2 Biogenetic Pathways to Gymnothelignans
3 Total Syntheses of Eupodienones
4 Total Syntheses of Eupomatilones
5 Total Synthesis of Dibenzocyclooctenes
6 Conclusions
Key words
total synthesis - biogenetic pathway - gymnothelignans - eupodienone - eupomatilone - dibenzocyclooctene
