Synthesis 2023; 55(13): 2011-2018
DOI: 10.1055/s-0042-1751433
paper

Visible-Light-Driven Iodine-Catalyzed Synthesis of Unsymmetrical Disulfides via Oxidative Coupling

Ming-Zhe Ren
,
Yan-Jun Fu
,
Bo-Sheng Zhang
,
Zheng-Jun Quan
,
Xi-Cun Wang
We are thankful for the financial support from the National Natural Science Foundation of China (nos. 22067018, 22061038) and the Key Talent Projects of Gansu Province (2019-39).


Abstract

Herein, a facile and environmentally friendly oxidative coupling reaction to obtain unsymmetrical disulfide compounds, without using metal or organic dyes as photocatalyst and only using a catalytic amount of iodine, was developed. Oxygen is used as oxidant in the reaction and the substrate scope is wide. A gram-scale synthesis also highlights the synthetic practicality of this photochemical strategy. Moreover, our mechanistic studies support the formation of disulfide products through free-radical coupling.

Supporting Information



Publikationsverlauf

Eingereicht: 29. Dezember 2022

Angenommen nach Revision: 22. Februar 2023

Artikel online veröffentlicht:
27. März 2023

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