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DOI: 10.1055/s-0042-1755381
Role of Homoeopathy in Managing Chronic Paronychia: A Pretest–Posttest Interventional Study
Abstract
Background Chronic paronychia (CP), one of the commonest recalcitrant nail disorders, is a troublesome source of considerable discomfort to the patients, which negatively affects the quality of life (QoL) mainly of the housewives reporting in the Indian subcontinent.
Objective The aim of this study is to assess the utility of individualised homoeopathic treatment (IHT) in managing painful episodes with the improvement in QoL of CP patients.
Method A pretest–posttest clinical study was conducted on 40 patients with CP. The Numeric Rating Scale (NRS) and Dermatology Life Quality Index (DLQI) were the outcome measures, assessed at baseline and after 2 months of IHT. Modified Naranjo Criteria (MNC) evaluated the possible causal attribution of IHT.
Results There was a statistically significant reduction in pain NRS score (8.89 ± 0.84 vs 2.97 ± 1.17; 95% confidence interval [CI] = 5.44–6.39; p < 0.01) as well as DLQI score (19.35 ± 2.95 vs 3.59 ± 1.99; 95% CI = 15.06–16.45; p < 0.01) among 37 patients. The large effect size derived (4.17) clinically, substantiates the beneficial effects in managing the painful episodes of CP. The MNC scores (7–10) ascertained the likelihood of improvement due to IHT.
Conclusion IHT significantly reduced the pains due to CP and improved the QoL. Further studies are warranted with enhanced methodology.
Statement of Ethics
Ethical clearance was obtained from IEC, Siliguri (Ref no.: 60/2018–19/CRU(H)/Ethical/Slg/07.08.2018) before initiation of the study and was prospectively registered in the Clinical Trials Registry – India (Trial registration: CTRI-REF/2019/04/025510). Informed consent was taken from all the participants who were part of the study. Necessary measures were taken to ensure the confidentiality and anonymity of patients.
Publikationsverlauf
Artikel online veröffentlicht:
29. Dezember 2022
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References
- 1 Rigopoulos D, Gregoriou S, Belyayeva E, Larios G, Kontochristopoulos G, Katsambas A. Efficacy and safety of tacrolimus ointment 0.1% vs. betamethasone 17-valerate 0.1% in the treatment of chronic paronychia: an unblinded randomized study. Br J Dermatol 2009; 160 (04) 858-860
- 2 Dulski A, Edwards CW. Paronychia. [Updated 2020 Aug 10]. [Internet] Treasure Island, FL: StatPearls Publishing; 2021: 20894
- 3 Hochman LG. Paronychia: more than just an abscess. Int J Dermatol 1995; 34 (06) 385-386
- 4 ICD-11 for Mortality and Morbidity Statistics. Accessed February 10, 2022. Accessed July 19, 2022 https://icd.who.int/browse11/l-m/en#/http://id.who.int/icd/entity/409382263
- 5 Paronychia - Symptoms, diagnosis and treatment | BMJ Best Practice. Accessed July 19, 2022 https://bestpractice-bmj.ccrhlibrary.in/topics/en-gb/350?q=Paronychia&c=recentlyviewed
- 6 Pierrart J, Delgrande D, Mamane W, Tordjman D, Masmejean EH. Acute felon and paronychia: antibiotics not necessary after surgical treatment. Prospective study of 46 patients. Hand Surg Rehabil 2016; 35 (01) 40-43
- 7 Jebson PJL. Infections of the fingertip. Paronychias and felons. Hand Clin 1998; 14 (04) 547-555 , viii
- 8 Rockwell PG. Acute and chronic paronychia. Am Fam Physician 2001; 63 (06) 1113-1116
- 9 Black JR. Paronychia. Clin Podiatr Med Surg 1995; 12 (02) 183-187
- 10 Bahunuthula RK, Thappa DM, Kumari R, Singh R, Munisamy M, Parija SC. Evaluation of role of Candida in patients with chronic paronychia. Indian J Dermatol Venereol Leprol 2015; 81 (05) 485-490
- 11 Belyayeva E, Gregoriou S, Chalikias J. et al. The impact of nail disorders on quality of life. Eur J Dermatol 2013; 23 (03) 366-371
- 12 Reich A, Szepietowski JC. Health-related quality of life in patients with nail disorders. Am J Clin Dermatol 2011; 12 (05) 313-320
- 13 Bednar MS, Lane LB. Eponychial marsupialization and nail removal for surgical treatment of chronic paronychia. J Hand Surg Am 1991; 16 (02) 314-317
- 14 Grover C, Bansal S, Nanda S, Reddy BSN, Kumar V. En bloc excision of proximal nail fold for treatment of chronic paronychia. Dermatol Surg 2006; 32 (03) 393-398 , discussion 398–399
- 15 Ferreira Vieira d'Almeida L, Papaiordanou F, Araújo Machado E, Loda G, Baran R, Nakamura R. Chronic paronychia treatment: square flap technique. J Am Acad Dermatol 2016; 75 (02) 398-403
- 16 Rich P. Nail cosmetics. Dermatol Clin 2006; 24 (03) 393-399
- 17 Fox PA, Tung MY. Human papillomavirus: burden of illness and treatment cost considerations. Am J Clin Dermatol 2005; 6 (06) 365-381
- 18 Relhan V, Goel K, Bansal S, Garg VK. Management of chronic paronychia. Indian J Dermatol 2014; 59 (01) 15-20
- 19 Herman PM, Craig BM, Caspi O. Is complementary and alternative medicine (CAM) cost-effective? A systematic review. BMC Complement Altern Med 2005; 5 (05) 11
- 20 Mathie RT. The research evidence base for homeopathy: a fresh assessment of the literature. Homeopathy 2003; 92 (02) 84-91
- 21 Haque S, Das D, Bhattacharya S, Sarkar T, Khuda-Bukhsh AR. Homeopathy - a safe, much less expensive, non-invasive, viable alternative for the treatment of patients suffering from loss of lumbar lordosis. J Pharmacopuncture 2016; 19 (04) 358-361
- 22 NABH. NABH Accreditation Standards for Homoeopathy. 2nd edition. New Delhi: NABH; 2016
- 23 Allen HC. Keynotes and Characteristics with Comparison of Some of the Leading Remedies of the Materia Medica with Bowel Nosodes. 15th impression. New Delhi: B Jain Publishers (P) Ltd; 2016
- 24 Boericke W. Boericke's New Manual of Homeopathic Materia Medica with Repertory. 37th edition. New Delhi: B Jain Publishers (P) Ltd;; 2016
- 25 Clarke JH. A Dictionary of Practical Materia Medica. Reprint ed. New Delhi: B Jain Publishers (P) Ltd; 1996
- 26 Kent JT. Lectures on Homoeopathic Materia Medica. Reprint ed. Nee Delhi: B Jain Publishers (P) Ltd.; 2012
- 27 Schroyens F. Repertorium Homeopathicum Syntheticum. Reprint 9. New Delhi: B Jain Publishers (P) Ltd; 2012
- 28 Murphy R. Homeopathic Medical Repertory: A Modern Alphabetical and Practical Repertory. 7th Reprint. New Delhi: B Jain Publishers (P) Ltd; 2009
- 29 PubMed. . Accessed July 19, 2022 https://pubmed.ncbi.nlm.nih.gov/.
- 30 Homeopathy Research Institute | HRI – CORE-Hom. Accessed July 19, 2022 https://www.hri-research.org/resources/research-databases/core-hom/
- 31 Google Scholar. . Accessed July 19, 2022 https://scholar.google.co.in/citations?user=9-Drb74AAAAJ&hl=en&scioq=google+scholar
- 32 AYUSH RESEARCH PORTAL. . Accessed July 19, 2022 https://ayushportal.nic.in/
- 33 Archive on Homoeopathy. . Search. Accessed July 19, 2022 http://aohindia.in/jspui/simple-search?query=paronychia
- 34 Anjana RM, Deepa M, Pradeepa R. et al; ICMR–INDIAB Collaborative Study Group. Prevalence of diabetes and prediabetes in 15 states of India: results from the ICMR-INDIAB population-based cross-sectional study. Lancet Diabetes Endocrinol 2017; 5 (08) 585-596
- 35 NAMASTE - Portal.
- 36 Kent JT. Lectures on Homeopathic Philosophy. 4th Reprint. New Delhi: B Jain Publishers; 1997
- 37 McCaffery M, Beebe A. Pain: Clinical manual for nursing practice. St Louis, MO: Mosby; 1989
- 38 Sloman R, Wruble AW, Rosen G, Rom M. Determination of clinically meaningful levels of pain reduction in patients experiencing acute postoperative pain. Pain Manag Nurs 2006; 7 (04) 153-158
- 39 Jesmin A, Sultana A, Saiful M, Bhuiyan I, Arafat SMY. Validation of Bangla Dermatology Life Quality Index among patients with psoriasis. J Pak Assoc Dermatol 2021; 31 (02) 165-172
- 40 Finlay AY, Khan GK. Dermatology Life Quality Index (DLQI)–a simple practical measure for routine clinical use. Clin Exp Dermatol 1994; 19 (03) 210-216
- 41 Basra MK, Fenech R, Gatt RMSM, Salek MS, Finlay AY. The Dermatology Life Quality Index 1994-2007: a comprehensive review of validation data and clinical results. Br J Dermatol 2008; 159 (05) 997-1035
- 42 Hongbo Y, Thomas CL, Harrison MA, Salek MS, Finlay AY. Translating the science of quality of life into practice: what do dermatology life quality index scores mean?. J Invest Dermatol 2005; 125 (04) 659-664
- 43 van Haselen RA. Homeopathic clinical case reports: development of a supplement (HOM-CASE) to the CARE clinical case reporting guideline. Complement Ther Med 2016; 25: 78-85
- 44 Naranjo CA, Busto U, Sellers EM. et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981; 30 (02) 239-245
- 45 Stub T, Salamonsen A, Alraek T. Is it possible to distinguish homeopathic aggravation from adverse effects? A qualitative study. Forsch Komplement Med 2012; 19 (01) 13-19
- 46 Stub T, Kristoffersen AE, Alræk T, Musial F, Steinsbekk A. Risk in homeopathy: Classification of adverse events and homeopathic aggravations–A cross sectional study among Norwegian homeopath patients. Complement Ther Med 2014; 23 (04) 535-543
- 47 Choubey G, Nahar L, Banerjee A, Roja V. Role of homoeopathy in the management of adhesive capsulitis: a pretest-posttest study. Indian J Res Homoeopath 2022; 16 (01) 31-40
- 48 Mathie RT, Van Wassenhoven M, Rutten ALB. et al. Model validity of randomised placebo-controlled trials of non-individualised homeopathic treatment. Homeopathy 2017; 106 (04) 194-202