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CC BY-NC-ND 4.0 · Arch Plast Surg 2022; 49(05): 656-662
DOI: 10.1055/s-0042-1756345
Hand/Peripheral Nerve: Review Article

Rare Tumors Causing Median Nerve Compression in Adults—A Narrative Review

Tinatin Natroshvili 
1   Department of Plastic and Reconstructive Surgery, Radboud University Medical Center, Nijmegen, The Netherlands
2   Department of Plastic and Reconstructive Surgery, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands
,
Kirsten Peperkamp 
1   Department of Plastic and Reconstructive Surgery, Radboud University Medical Center, Nijmegen, The Netherlands
2   Department of Plastic and Reconstructive Surgery, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands
,
Masoud A. Malyar 
2   Department of Plastic and Reconstructive Surgery, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands
,
David Wijnberg
2   Department of Plastic and Reconstructive Surgery, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands
,
Erwin P. Heine 
2   Department of Plastic and Reconstructive Surgery, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands
,
Erik T. Walbeehm 
1   Department of Plastic and Reconstructive Surgery, Radboud University Medical Center, Nijmegen, The Netherlands
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Abstract

The median nerve can be compressed due to a tumor along the course of the median nerve, causing typical compression symptoms or even persistence or recurrence after an operation. The aim of this review is to provide a comprehensive overview of rare tumors described in recent publications that cause median nerve compression and to evaluate treatment options.

The PubMed, Embase, and Web of Science databases were searched for studies describing median nerve compression due to a tumor in adults, published from the year 2000 and written in English. From 94 studies, information of approximately 100 patients have been obtained.

Results The rare tumors causing compression were in 32 patients located at the carpal tunnel, in 21 cases in the palm of the hand, and 28 proximal from the carpal tunnel. In the other cases the compression site extended over a longer trajectory. There were 37 different histological types of lesions. Complete resection of the tumor was possible in 58 cases. A total of 8 patients presented for the second time after receiving initial therapy. During follow-up, three cases of recurrence were reported with a mean follow-up period of 11 months.

The most common published cause of median nerve compression is the lipofibromatous hamartoma. Besides the typical sensory and motor symptoms of median nerve compression, a thorough physical examination of the complete upper extremity is necessary to find any swelling or triggering that might raise suspicion of the presence of a tumor.

Keywords

median neuropathy - neoplasms - rare diseases

Ethical Approval

This article does not contain any studies with human or animal subjects performed by the any of the authors. For this type of study informed consent is not required.


Authors' Contributions

All the authors have approved the final contents of the submission, been actively involved in the planning and enactment of the study, and have also assisted with the preparation of the submitted article.


Supplementary Material



Publication History

Received: 28 April 2021

Accepted: 11 July 2022

Article published online:
23 September 2022

© 2022. The Korean Society of Plastic and Reconstructive Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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