CC BY-NC-ND 4.0 · Arch Plast Surg 2022; 49(05): 689-695
DOI: 10.1055/s-0042-1756348
Extremity/Lymphedema: Original Article

Lymphaticovenular Anastomosis: Superficial Venous Anatomical Approach

1   Plastic and Reconstructive Unit, Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
,
1   Plastic and Reconstructive Unit, Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
› Institutsangaben

Abstract

Background Lymphaticovenular anastomosis (LVA) is an effective, functional treatment for limb lymphedema. This study reports an alternative surgical approach to lymphedema treatment without the use of indocyanine green mapping.

Methods A retrospective analysis was performed on 29 consecutive lymphedema patients who underwent LVAs from January 2015 to December 2020, whereby incisions were made along the anatomy of the superficial venous systems in both upper and lower extremities around the joint areas. The evaluation included qualitative assessments and quantitative volumetric analyses.

Result The mean number of anastomoses was 3.07, and the operative time was 159.55 minutes. Symptom improvement was recorded in 86.21% of the patients, with a mean volume reduction of 32.39%. The lymphangitis episodes decreased from 55.17% before surgery to 13.79% after surgery, and the median number of lymphangitis episodes per year decreased from 1 before surgery to 0 after surgery.

Conclusions The superficial venous anatomical approach is an easy way to start a lymphedema practice using LVA without other advanced surgical equipment. With this reliable technique, microsurgeons can perform LVA procedures and achieve good results.

Authors' Contributions

Conceptualization: K.W., P.S. Data curation: K.W. Methodology: K.W., P.S. Project administration: K.W. Writing original draft: K.W. Writing – review & editing: K.W., P.S. All authors read and approved the final manuscript.


Ethical Approval

The study was approved by the Khon Kaen University Ethics Committee for Human Research (IRB No. HE641259) and performed in accordance with the principles of the Declaration of Helsinki. The informed consent was waived because this study design is a retrospective chart review.


Patient Consent

Patients provided written consent for the use of their images.




Publikationsverlauf

Eingereicht: 01. Oktober 2021

Angenommen: 26. Juli 2022

Artikel online veröffentlicht:
23. September 2022

© 2022. The Korean Society of Plastic and Reconstructive Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 
  • References

  • 1 Brorson H, Ohlin K, Olsson G, Nilsson M. Adipose tissue dominates chronic arm lymphedema following breast cancer: an analysis using volume rendered CT images. Lymphat Res Biol 2006; 4 (04) 199-210
  • 2 Executive Committee. The diagnosis and treatment of peripheral lymphedema: 2009 Consensus Document of the International Society of Lymphology. Lymphology 2016; 49 (04) 170-184 PubMed
  • 3 Schook CC, Mulliken JB, Fishman SJ, Grant FD, Zurakowski D, Greene AK. Primary lymphedema: clinical features and management in 138 pediatric patients. Plast Reconstr Surg 2011; 127 (06) 2419-2431
  • 4 Yamamoto T, Yoshimatsu H, Narushima M, Yamamoto N, Hayashi A, Koshima I. Indocyanine green lymphography findings in primary leg lymphedema. Eur J Vasc Endovasc Surg 2015; 49 (01) 95-102
  • 5 Chang DW, Masia J, Garza III R, Skoracki R, Neligan PC. Lymphedema: Surgical and medical therapy. Plast Reconstr Surg 2016; 138 (3, suppl) 209S-218S
  • 6 Yamamoto T, Yamamoto N, Kageyama T. et al. Technical pearls in lymphatic supermicrosurgery. Glob Health Med 2020; 2 (01) 29-32
  • 7 Damstra RJ, Voesten HGJ, van Schelven WD, van der Lei B. Lymphatic venous anastomosis (LVA) for treatment of secondary arm lymphedema. A prospective study of 11 LVA procedures in 10 patients with breast cancer related lymphedema and a critical review of the literature. Breast Cancer Res Treat 2009; 113 (02) 199-206
  • 8 Mortimer P. Investigation and management of lymphoedema. Vascular Medicine Review 1990; 1: 1-20
  • 9 Koshima I, Inagawa K, Etoh K, Moriguchi T. Supramicrosurgical lymphaticovenular anastomosis for the treatment of lymphedema in the extremities [in Japanese]. Nippon Geka Gakkai Zasshi 1999; 100 (09) 551-556
  • 10 Koshima I, Inagawa K, Urushibara K, Moriguchi T. Supermicrosurgical lymphaticovenular anastomosis for the treatment of lymphedema in the upper extremities. J Reconstr Microsurg 2000; 16 (06) 437-442
  • 11 Retik AB, Perlmutter AD, Harrison JH. Communications between lymphatics and veins involving the portal circulation. Am J Surg 1965; 109: 201-205 PubMed
  • 12 Pressman JL, Burtz MV, Shafer L. Further observations related to direct communications between lymph nodes and veins. Surg Gynecol Obstet. 1964; 119: 984-990 PubMed
  • 13 Yamamoto T, Narushima M, Doi K. et al. Characteristic indocyanine green lymphography findings in lower extremity lymphedema: the generation of a novel lymphedema severity staging system using dermal backflow patterns. Plast Reconstr Surg 2011; 127 (05) 1979-1986
  • 14 Yamamoto T, Yamamoto N, Yoshimatsu H, Hayami S, Narushima M, Koshima I. Indocyanine green lymphography for evaluation of genital lymphedema in secondary lower extremity lymphedema patients. J Vasc Surg Venous Lymphat Disord 2013; 1 (04) 400-405.e1
  • 15 Yamamoto T, Narushima M, Yoshimatsu H. et al. Dynamic Indocyanine Green (ICG) lymphography for breast cancer-related arm lymphedema. Ann Plast Surg 2014; 73 (06) 706-709
  • 16 Campisi C, Boccardo F. Microsurgical techniques for lymphedema treatment: derivative lymphatic-venous microsurgery. World J Surg 2004; 28 (06) 609-613
  • 17 Seki Y, Yamamoto T, Yoshimatsu H. et al. The superior-edge-of-the-knee incision method in lymphaticovenular anastomosis for lower extremity lymphedema. Plast Reconstr Surg 2015; 136 (05) 665e-675e
  • 18 Sander AP, Hajer NM, Hemenway K, Miller AC. Upper-extremity volume measurements in women with lymphedema: a comparison of measurements obtained via water displacement with geometrically determined volume. Phys Ther 2002; 82 (12) 1201-1212
  • 19 Drobot A, Bez M, Abu Shakra I. et al. Microsurgery for management of primary and secondary lymphedema. J Vasc Surg Venous Lymphat Disord 2021; 9 (01) 226-233.e1
  • 20 Tidhar D, Armer JM, Deutscher D, Shyu CR, Azuri J, Madsen R. Measurement issues in anthropometric measures of limb volume change in persons at risk for and living with lymphedema: a reliability study. J Pers Med 2015; 5 (04) 341-353
  • 21 Karges JR, Mark BE, Stikeleather SJ, Worrell TW. Concurrent validity of upper-extremity volume estimates: comparison of calculated volume derived from girth measurements and water displacement volume. Phys Ther 2003; 83 (02) 134-145
  • 22 Yamamoto T, Yamamoto N, Hara H, Mihara M, Narushima M, Koshima I. Upper extremity lymphedema index: a simple method for severity evaluation of upper extremity lymphedema. Ann Plast Surg 2013; 70 (01) 47-49
  • 23 Yamamoto T, Matsuda N, Todokoro T. et al. Lower extremity lymphedema index: a simple method for severity evaluation of lower extremity lymphedema. Ann Plast Surg 2011; 67 (06) 637-640
  • 24 Koshima I, Kawada S, Moriguchi T, Kajiwara Y. Ultrastructural observations of lymphatic vessels in lymphedema in human extremities. Plast Reconstr Surg 1996; 97 (02) 397-405 , discussion 406–407
  • 25 Chang DW, Suami H, Skoracki R. A prospective analysis of 100 consecutive lymphovenous bypass cases for treatment of extremity lymphedema. Plast Reconstr Surg 2013; 132 (05) 1305-1314
  • 26 Suami H, Chang DW, Yamada K, Kimata Y. Use of indocyanine green fluorescent lymphography for evaluating dynamic lymphatic status. Plast Reconstr Surg 2011; 127 (03) 74e-76e
  • 27 Kitai T, Inomoto T, Miwa M, Shikayama T. Fluorescence navigation with indocyanine green for detecting sentinel lymph nodes in breast cancer. Breast Cancer 2005; 12 (03) 211-215
  • 28 Unno N, Inuzuka K, Suzuki M. et al. Preliminary experience with a novel fluorescence lymphography using indocyanine green in patients with secondary lymphedema. J Vasc Surg 2007; 45 (05) 1016-1021
  • 29 Ogata F, Narushima M, Mihara M, Azuma R, Morimoto Y, Koshima I. Intraoperative lymphography using indocyanine green dye for near-infrared fluorescence labeling in lymphedema. Ann Plast Surg 2007; 59 (02) 180-184
  • 30 Yamamoto T, Matsuda N, Doi K. et al. The earliest finding of indocyanine green lymphography in asymptomatic limbs of lower extremity lymphedema patients secondary to cancer treatment: the modified dermal backflow stage and concept of subclinical lymphedema. Plast Reconstr Surg 2011; 128 (04) 314e-321e
  • 31 Narushima M, Yamamoto T, Ogata F, Yoshimatsu H, Mihara M, Koshima I. Indocyanine green lymphography findings in limb lymphedema. J Reconstr Microsurg 2016; 32 (01) 72-79
  • 32 Suzuki Y, Sakuma H, Yamazaki S. Comparison of patency rates of lymphaticovenous anastomoses at different sites for lower extremity lymphedema. J Vasc Surg Venous Lymphat Disord 2019; 7 (02) 222-227
  • 33 O'Brien BMC, Mellow CG, Khazanchi RK, Dvir E, Kumar V, Pederson WC. Long-term results after microlymphaticovenous anastomoses for the treatment of obstructive lymphedema. Plast Reconstr Surg 1990; 85 (04) 562-572
  • 34 Pereira N, Lee YH, Suh Y. et al. Cumulative experience in lymphovenous anastomosis for lymphedema treatment: the learning curve effect on the overall outcome. J Reconstr Microsurg 2018; 34 (09) 735-741
  • 35 Mihara M, Hara H, Tange S. et al. Multisite lymphaticovenular bypass using supermicrosurgery technique for lymphedema management in lower lymphedema cases. Plast Reconstr Surg 2016; 138 (01) 262-272