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CC BY 4.0 · J Neuroanaesth Crit Care 2023; 10(01): 051-053
DOI: 10.1055/s-0042-1756433
Case Report

Malignant Hyperthermia Like Manifestations during Management of Refractory Status Epilepticus

Deepti Srinivas
1   Department of Neuroanaesthesia and Critical Care, Apollo Hospitals, Bangalore, Karnataka, India
,
Venkatesh Keshavan
2   Department of Anaesthesiology and Critical Care, Khoula Hospital, Muscat, Oman
,
Vikram Kamath
3   Department of Neurology, Apollo Hospitals, Bangalore, Karnataka, India
,
Manju Manmadhan
4   Department of Anaesthesia and Neurocritical Care, Rajagiri Hospital, Kochi, Kerala, India
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Abstract

Management of refractory status epilepticus is challenging for a neurointensivist consequent to systemic complexities associated with various drugs and modalities involved in its treatment. We report one such case that manifested with multiple signs of malignant hyperthermia following use of isoflurane to control seizures. However, the delayed and random occurrence of the signs and negative genetic test report raises doubts regarding the final diagnosis. Delayed presentation of malignant hyperthermia has been reported earlier. Unavailability of dantrolene sodium handily is a major hurdle in treating such cases. We enumerate management of the patient in our intensive care unit.

Keywords

status epilepticus - malignant hyperthermia - delayed malignant hyperthermia - isoflurane


Publikationsverlauf

Artikel online veröffentlicht:
12. Mai 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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