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CC BY 4.0 · World J Nucl Med 2023; 22(01): 040-042
DOI: 10.1055/s-0042-1757281
Case Report

Is Further Evaluation of Areas with Faint MDP Uptake Needed in Individuals with Oligo-Metastatic Prostatic Adenocarcinoma?

Anshul Sharma
1   Department of Nuclear Medicine, Homi Bhabha Cancer Hospital and Research Centre, Punjab, India
,
Ankur Dwivedi
2   Department of Radiodiagnosis, Homi Bhabha Cancer Hospital and Research Centre, Punjab, India
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Abstract

A 42-year-old male patient with high-risk prostate adenocarcinoma underwent baseline 99mTc-methylene diphosphonate skeletal scintigraphy, which revealed two skeletal metastases and an area of faint radiotracer uptake in the left femoral shaft. In view of oligo-metastatic nature of the disease in the bone scan and the young age of the patient, he was a candidate for metastases-directed treatment. Single photon emission computed tomography (SPECT)/CT was performed to further characterize this lesion. It was revealed to be a small soft tissue density lesion within the fatty bone marrow density, suggesting bone marrow involvement. A more sensitive evaluation of such areas with faint radiotracer uptake may be needed in high-risk prostate cancer patients where access to advanced modalities is limited. Their significance will also need reassessment as their detection will improve with technological advancements.

Keywords

high-risk prostate cancer - 99mTc-MDP - skeletal scintigraphy - bone marrow metastasis - oligometastatic disease

Informed Consent

Permission was taken from the patient before submitting this case study.




Publication History

Article published online:
28 October 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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