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CC BY 4.0 · J Neuroanaesth Crit Care 2023; 10(01): 056-059
DOI: 10.1055/s-0042-1757912
Case Report

Peripartum Cerebral Angiopathy

Amr Sallam
1   Department of Anaesthesiology and Critical Care Medicine, Beaumont Hospital, Dublin, Ireland
,
Sebastian R. McWilliams
2   Department of Neuroradiology, Beaumont Hospital, Dublin, Ireland
,
Karl Boyle
3   Department of Stroke Medicine, Beaumont Hospital, Dublin, Ireland
,
Caroline M. Larkin
1   Department of Anaesthesiology and Critical Care Medicine, Beaumont Hospital, Dublin, Ireland
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Abstract

Peripartum cerebral angiopathy (PCA) is a rare cerebrovascular disorder of unclear etiology that typically occurs in the first postpartum week. The aim of this case series is to present seven cases of PCA and the associated outcomes. Two of the cases were typical of a reversible cerebral vasoconstriction syndrome (RCVS) and had no long-term sequelae. Five of the cases involved intraparenchymal hemorrhage in the absence of an underlying vascular lesion, with three of the five cases having associated cerebral vasoconstriction. None of the patients had a documented history of preeclampsia or hypertension during pregnancy. It has been suggested that there is pathophysiological overlap between PCA and eclampsia and RCVS. There is limited evidence in the literature in this regard and, in most cases, treatment has been supportive only. As a condition, PCA may be under-recognized in the neurocritical care setting. Increased awareness of this condition, its manifestations, and options for management may optimize outcomes.

Keywords

peripartum - postpartum angiopathy - reversible cerebral vasoconstriction syndrome - cerebral intraparenchymal hemorrhage


Publikationsverlauf

Artikel online veröffentlicht:
24. April 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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