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DOI: 10.1055/s-0042-1758368
Microbiological Profile of Periprosthetic Knee Infections in a Brazilian Unified Health System Hospital Specialized in Highly Complex Orthopedic Surgeries[*]
Artikel in mehreren Sprachen: português | EnglishFinancial Support There was no financial support from public, commercial, or nonprofit sources.

Abstract
Objective We studied the microbiological profile of periprosthetic knee infections treated in a Brazilian tertiary hospital.
Methods The study included all patients undergoing revision surgery for total knee arthroplasty (RTKA) between November 2019 and December 2021, with a diagnosis of periprosthetic infection confirmed per the 2018 International Consensus Meeting (ICM) criteria.
Results Sixty-two patients had a periprosthetic joint infection (PJI) per the 2018 ICM criteria. Cultures were monomicrobial in 79% and polymicrobial in 21% of cases. The most frequent bacterium in microbiological tissue and synovial fluid cultures was Staphylococcus aureus, observed in 26% of PJI patients. Periprosthetic joint infection with negative cultures occurred in 23% of patients.
Conclusion Our results show the following: i) a high prevalence of Staphylococcus as an etiological agent for knee PJI; ii) a high incidence of polymicrobial infections in early infections; iii) the occurrence of PJI with negative cultures in approximately one fourth of the subjects.
Keywords
arthroplasty, replacement, knee - postoperative complications - intraarticular injections - prosthesis-related infections* Study developed at Instituto Nacional de Traumatologia e Ortopedia (INTO), Rio de Janeiro, Brazil.
Publikationsverlauf
Eingereicht: 18. April 2022
Angenommen: 12. September 2022
Artikel online veröffentlicht:
29. Juni 2023
© 2023. Sociedade Brasileira de Ortopedia e Traumatologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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