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Am J Perinatol 2024; 41(S 01): e917-e921
DOI: 10.1055/s-0042-1759705
Original Article

Quality Improvement Initiative for Aspirin Screening and Prescription Rates for Preeclampsia Prevention in an Outpatient Obstetric Clinic

Natasha R. Kumar
1   Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
,
Sedona E. Speedy
2   Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
,
Jing Song
3   Department of Preventive Medicine, Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois
,
Leah J. Welty
3   Department of Preventive Medicine, Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois
,
Arjeme D. Cavens
2   Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
› Author Affiliations Funding This quality improvement initiative was supported by a 2020 AMAG Pharmaceuticals Research Grant.
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Abstract

Objective Hypertensive disorders of pregnancy (HDP) impact 10% of pregnancies in the United States and cause adverse maternal and neonatal outcomes such as prematurity and low birth weight. Aspirin administration to at-risk individuals during pregnancy can reduce risk of HDP.

Study Design Define-Measure-Assess-Improve-Control methodology was utilized to improve aspirin screening in an outpatient obstetric clinic. Retrospective cohort analysis compared outcome metrics pre- and postimplementation by using logistic regression models, adjusting for race and insurance. Key informant interviews and process mapping identified barriers to aspirin screening. A multidisciplinary team implemented low-cost strategies such as provider education, additional screening by ancillary staff, automated electronic reminders, and standardized patient counseling.

Results Over 6 months, the screening rate improved from 62.5 to 92.0% (adjusted odds ratio [aOR] = 6.89, 95% confidence interval [CI]: 3.30–14.43). The prescription rate for patients correctly identified to be eligible for aspirin improved from 66.7 to 82.4% (aOR = 1.96, 95% CI: 0.88–4.35).

Conclusion Comprehensive, tailored quality improvement efforts can significantly increase aspirin screening and prescription, which may decrease maternal and neonatal morbidity due to HDP.

Key Points

  • Initiative improved overall and correct screening rates.

  • Initiative increased provider knowledge of eligibility.

  • Low-cost interventions can have high impact over short time interval.

Keywords

preeclampsia - hypertensive disorders of pregnancy - aspirin - quality improvement - implementation science


Publication History

Received: 03 February 2022

Accepted: 01 November 2022

Article published online:
30 December 2022

© 2022. Thieme. All rights reserved.

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