Single-Center Experience of Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertension: The Results from the Tabriz University Medical Sciences (TUMS) CTEPH Program

Rezayat Parvizi; Eisa Bilehjani; Babak Mahmoudian; Ata Koohi; Hooriah Shojaan; Khalil Ansarin; Farid Rashidi

doi:10.1055/s-0042-1760204

The Thoracic and Cardiovascular Surgeon, Inhaltsverzeichnis

Thorac Cardiovasc Surg 2023; 71(05): 407-412
DOI: 10.1055/s-0042-1760204

Original Cardiovascular

Single-Center Experience of Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertension: The Results from the Tabriz University Medical Sciences (TUMS) CTEPH Program

Rezayat Parvizi

¹Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

,

Eisa Bilehjani

¹Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

,

Babak Mahmoudian

²Medical Radiation Sciences Research Team, Tabriz University of Medical Sciences, Tabriz, Iran

,

Ata Koohi

³Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

,

Hooriah Shojaan

³Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

,

Khalil Ansarin

³Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

,

Farid Rashidi

³Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

› Institutsangaben

Abstract

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Abstract

Introduction Pulmonary endarterectomy (PEA) remains the preferred and potentially curative option for patients with chronic thromboembolic pulmonary hypertension (CTEPH). This study aimed to report the results of PEA for CTEPH in a tertiary center in Tabriz, Iran.

Methods We analyzed the results of 42 CTEPH patients undergoing PEA, who were enrolled in the Tabriz University of Medical Sciences (TUMS-CTEPH) from January 2016 to October 2020. The main outcome measures included the New York Heart Association (NYHA) functional classification, the 6-Minute Walk Distance, hemodynamic measures in right heart catheterization, morbidity, and mortality.

Results There was a significant improvement in the NYHA function class (2.6 ± 0.5 vs 1.1 ± 0.34), mean pulmonary arterial pressure (47.1 ± 13 vs 27.9 ± 8 mm Hg), cardiac output (4.3 ± 1.06 vs 5.9 ± 1.2 L/min), and pulmonary vascular resistance (709.4 ± 297.5 vs 214 ± 77 dyn s/cm⁵). Fifteen patients (35%) developed complications. The most common complication (10 [23%]) was reperfusion injury. Also, postsurgical mortality was 4% during hospital admission and 1-year follow-up.

Conclusion This is the first single-center report of PEA from Iran. Post-PEA and 1-year survival were acceptable as a referral center. PEA can be performed safe with low mortality. Greater awareness of PEA and patients' access to experienced CTEPH centers are important issues.

Keywords

pulmonary hypertension - thromboendarterectomy - chronic thromboembolism

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Referenzen

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