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DOI: 10.1055/s-0043-108647
Successful endoscopic suturing of esophageal perforation after surgical suturing failure
Publication History
Publication Date:
05 July 2017 (online)
![](https://www.thieme-connect.de/media/endoscopy/201709/lookinside/thumbnails/0021_10-1055-s-0043-108647-1.jpg)
Esophageal perforations still present a life-threatening situation. Although stent insertion and clips have a proven high success rate, some perforations are extremely challenging and persist despite several attempts using different closure techniques. Recently a new endoscopic suturing system (OverStitch; Apollo Endosurgery Inc., Austin, Texas, USA) has been introduced for full-thickness tissue approximation. We report two cases of successful suturing of an esophageal perforation using the OverStitch device, after the failure of surgical suturing.
The first patient was an 87-year-old woman with a wide perforation (35 mm long × 25 mm) of the mid-esophagus due to Boerhaave syndrome. She was initially treated surgically but the leak reappeared within the first postoperative week. Closure was attempted endoscopically with hemostatic clips (Instinct Clips; Cook Medical Inc., Bloomington, Indiana, USA), but this also failed. After previous clips had been removed, the margins of the defect were cauterized using argon plasma and three interrupted sutures were applied using the OverStitch device ([Video 1]). Subsequent contrast medium showed no leaks.
Video 1 Closure of an esophageal perforation using the OverStitch device (Apollo Endosurgery Inc., Austin, Texas, USA). A Large mid-esophageal defect was present after a failed attempt at surgical closure. After complete cleaning of the para-esophageal cavity, the margins of the defect were cauterized using argon plasma before suturing. Then, interrupted sutures were applied using the OverStitch device, and the closure of the esophageal defect was finally achieved.
Quality:
Follow-up examination with contrast medium (first post-treatment week), showed a small persistent leak. The leak was smaller than the initial defect (about 20 mm long × 20 mm). Three interrupted sutures were applied using OverStitch, and contrast medium showed no residual leak. A metal fully covered stent, 100 × 14 mm (Niti-S; Taewoong Medical, Gyeonggi-do, South Korea) was finally placed. After 1 month, the stent was removed and the defect had closed successfully ([Fig. 1]).
![](https://www.thieme-connect.de/media/endoscopy/201709/thumbnails/10-1055-s-0043-108647-i0021cl1.jpg)
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The second case was a 73-year-old woman with an esophageal perforation caused by the impaction of a turkey bone. The defect was initially treated by surgery but the contrast medium 2 weeks after surgery showed a persistent leak. Endoscopy revealed a 30 mm long × 25 mm perforation in the mid-esophagus. The margins were cauterized using argon plasma. Three interrupted sutures were applied using the Apollo OverStitch. A metal fully covered stent, 100 × 20 mm (Niti-S; Taewoong Medical) was placed to cover the suture. However, post-treatment radiology at 1 week showed a smaller persistent esophageal defect. After removal of the stent, the defect was successfully closed with three interrupted sutures at a second session, and a metal fully covered stent, 100 × 22 mm (Niti-S; Taewoong Medical) was placed. Closure was radiologically confirmed 4 weeks later.
Although larger series are needed to confirm our initial experience, these cases suggest that OverStitch is a promising endoscopic device for closing large esophageal perforations, even after surgical failure.
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