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Endoscopy 2018; 50(01): 63-68
DOI: 10.1055/s-0043-120666
Innovations and brief communications
© Georg Thieme Verlag KG Stuttgart · New York

Feasibility, safety, and diagnostic yield of the Extra Wide Angle View (EWAVE) colonoscope for the detection of colorectal lesions

Maxime E. S. Bronzwaer
1   Department of Gastroenterology and Hepatology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
,
Evelien Dekker
1   Department of Gastroenterology and Hepatology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
2   Department of Endoscopy, Bergman Inwendige Zorg Amsterdam (IZA), Amsterdam, The Netherlands
,
Vincens Weingart
3   Medical Department, Klinikum Garmisch-Partenkirchen, Ludwig-Maximilians University, Garmisch-Partenkirchen, Germany
,
Stefan Groth
4   Department of Interdisciplinary Endoscopy, University Hospital Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany
,
Mathieu Pioche
5   Department of Endoscopy and Gastroenterology, Hôpital Edouard Herriot, University of Lyon, Lyon, France
,
Jérôme Rivory
5   Department of Endoscopy and Gastroenterology, Hôpital Edouard Herriot, University of Lyon, Lyon, France
,
Torsten Beyna
6   Department of Gastroenterology and Hepatology, Evangelischen Krankenhaus Düsseldorf, Düsseldorf, Germany
,
Horst Neuhaus
6   Department of Gastroenterology and Hepatology, Evangelischen Krankenhaus Düsseldorf, Düsseldorf, Germany
,
Thierry Ponchon
5   Department of Endoscopy and Gastroenterology, Hôpital Edouard Herriot, University of Lyon, Lyon, France
,
Hans Allescher
3   Medical Department, Klinikum Garmisch-Partenkirchen, Ludwig-Maximilians University, Garmisch-Partenkirchen, Germany
,
Paul Fockens
1   Department of Gastroenterology and Hepatology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
2   Department of Endoscopy, Bergman Inwendige Zorg Amsterdam (IZA), Amsterdam, The Netherlands
,
Thomas Rösch
4   Department of Interdisciplinary Endoscopy, University Hospital Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany
› Author AffiliationsTRIAL REGISTRATION: Prospective Multi-Center Cohort Study NTR 4536 at trialregister.nl
Further Information

Publication History

submitted 27 March 2017

accepted after revision 09 July 2017

Publication Date:
13 November 2017 (online)

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Abstract

Background and study aims The adenoma detection rate (ADR) of conventional colonoscopy can still be improved. We conducted a prospective multicenter cohort study to assess the feasibility, safety, and diagnostic yield of the Extra Wide Angle View (EWAVE) colonoscope, which offers a 235° view obtained from a forward-viewing and two lateral backward-viewing lenses incorporated into one image.

Patients and methods The study was performed between November 2015 and June 2016. EWAVE colonoscopy was performed in patients with an increased risk of colorectal cancer by experienced and EWAVE-trained endoscopists (≥ 500 colonoscopies, ≥ 10 with the EWAVE system).

Results A total of 193 patients underwent EWAVE colonoscopy. The cecal intubation rate was 97.4 %. EWAVE colonoscopy had a polyp detection rate (PDR) of 61.1 % (118 /193), ADR of 39.9 % (77 /193), and advanced ADR of 13.5 % (26 /193). No adverse events occurred.

Conclusions EWAVE colonoscopy is feasible and safe. The ADR appears comparable to those achieved with conventional colonoscopes in similar patient populations. To further elucidate the additional benefits of wide-angle-view colonoscopes, randomized trials would be required.

 

  • References

  • 1 Zauber AG, Winawer SJ, O'Brien MJ. et al. Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths. NEJM 2012; 366: 687-696
    CrossrefPubMedGoogle Scholar
  • 2 van Rijn JC, Reitsma JB, Stoker J. et al. Polyp miss rate determined by tandem colonoscopy: a systematic review. Am J Gastroenterol 2006; 101: 343-350
    CrossrefPubMedGoogle Scholar
  • 3 Brenner H, Chang-Claude J, Seiler CM. et al. Interval cancers after negative colonoscopy: population-based case-control study. Gut 2012; 61: 1576-1582
    CrossrefPubMedGoogle Scholar
  • 4 Dik VK, Moons LM, Siersema PD. Endoscopic innovations to increase the adenoma detection rate during colonoscopy. World J Gastroenterol 2014; 20: 2200-2211
    CrossrefPubMedGoogle Scholar
  • 5 Uraoka T, Tanaka S, Oka S. et al. Feasibility of a novel colonoscope with extra-wide angle of view: a clinical study. Endoscopy 2015; 47: 444-448
    Article in Thieme ConnectPubMedGoogle Scholar
  • 6 Schlemper RJ, Riddell RH, Kato Y. et al. The Vienna classification of gastrointestinal epithelial neoplasia. Gut 2000; 47: 251-255
    CrossrefPubMedGoogle Scholar
  • 7 Deenadayalu VP, Chadalawada V, Rex DK. 170 degrees wide-angle colonoscope: effect on efficiency and miss rates. Am J Gastroenterol 2004; 99: 2138-2142
    CrossrefPubMedGoogle Scholar
  • 8 Pellise M, Fernandez-Esparrach G, Cardenas A. et al. Impact of wide-angle, high-definition endoscopy in the diagnosis of colorectal neoplasia: a randomized controlled trial. Gastroenterology 2008; 135: 1062-1068
    CrossrefPubMedGoogle Scholar
  • 9 Gralnek IM, Siersema PD, Halpern Z. et al. Standard forward-viewing colonoscopy versus full-spectrum endoscopy: an international, multicentre, randomised, tandem colonoscopy trial. Lancet Oncol 2014; 15: 353-360
    CrossrefPubMedGoogle Scholar
  • 10 Hassan C, Senore C, Radaelli F. et al. Full-spectrum (FUSE) versus standard forward-viewing colonoscopy in an organised colorectal cancer screening programme. Gut DOI: 10.1136/gutjnl-2016-311906.
    CrossrefPubMedGoogle Scholar
  • 11 Barclay RL, Vicari JJ, Doughty AS. et al. Colonoscopic withdrawal times and adenoma detection during screening colonoscopy. NEJM 2006; 355: 2533-2541
    CrossrefPubMedGoogle Scholar
  • 12 Lee TJ, Blanks RG, Rees CJ. et al. Longer mean colonoscopy withdrawal time is associated with increased adenoma detection: evidence from the Bowel Cancer Screening Programme in England. Endoscopy 2013; 45: 20-26
    Article in Thieme ConnectPubMedGoogle Scholar
  • 13 Belderbos TD, Grobbee EJ, van Oijen MG. et al. Comparison of cecal intubation and adenoma detection between hospitals can provide incentives to improve quality of colonoscopy. Endoscopy 2015; 47: 703-709
    Article in Thieme ConnectPubMedGoogle Scholar
  • 14 le Clercq CM, Mooi RJ, Winkens B. et al. Temporal trends and variability of colonoscopy performance in a gastroenterology practice. Endoscopy 2016; 48: 248-255
    Article in Thieme ConnectPubMedGoogle Scholar
  • 15 Chin M, Karnes W, Jamal MM. et al. Use of the Endocuff during routine colonoscopy examination improves adenoma detection: A meta-analysis. World J Gastroenterol 2016; 22: 9642-9649
    CrossrefPubMedGoogle Scholar