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Transfusionsmedizin 2019; 9(01): 29-36
DOI: 10.1055/s-0043-121421
Praxistipp
Georg Thieme Verlag KG Stuttgart · New York

Behandlung von Spenderreaktionen bei präparativen Hämapheresen

Treatment of Donor Reactions in Preparative Hemaphereses
Jörg Martens
Institut für Transfusionsmedizin, Medizinische Hochschule Hannover, Hannover
,
Hans-Gert Heuft
Institut für Transfusionsmedizin, Medizinische Hochschule Hannover, Hannover
› Institutsangaben
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Publikationsverlauf

Publikationsdatum:
21. März 2019 (online)

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Zusammenfassung

Präparative Hämapheresen sind in vielen transfusionsmedizinischen Einrichtungen Standardverfahren zur modernen Herstellung von Blutprodukten. Sie kommen jährlich weltweit millionenfach zum Einsatz. Spenderreaktionen im Rahmen von präparativen Hämapheresen bei gesunden unverwandten Spendern sind dank moderner Apheresetechnik und hohen Prozessstandards heute ganz überwiegend als mild und klinisch nicht signifikant einzustufen. Die Kenntnis dieser, aber auch der seltenen schwerwiegenden Reaktionen, ihrer Symptome und ihrer Behandlung ist wichtig, um Spendersicherheit und Spendercompliance zu gewährleisten und Verfahrensabbrüche zu reduzieren bzw. zu vermeiden.

Abstract

Preparative hemaphereses are millionfold standard procedures for modern blood component production in many transfusion medicine establishments worldwide. Based on modern apheresis machine technique and high procedure standards the large majority of donor reactions in preparative hemaphereses are usually mild and clinically insignificant. Nevertheless, it is important to be familiar with typical and with severe donor reactions, with their symptoms and their medical treatment to assure donor safety and donor compliance and to reduce or avoid hemapheresis discontinuations.

Schlüsselwörter

Hämapheresen - Punktionskomplikationen - Zitratreaktionen - Kreislaufreaktionen - Spendercompliance - Sofortmaßnahmen - Operatorinterventionen - ärztliche Interventionen

Key words

haemaphereses - blood access injuries - immediate actions - operator interventions - physiciansʼ interventions - donor compliance
 

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