Das Mikrobiom – die unplanbare Größe zukünftiger Therapien

Achim G. Beule

doi:10.1055/s-0043-122301

Laryngo-Rhino-Otologie, Table of Contents

CC BY-NC-ND 4.0 · Laryngorhinootologie 2018; 97(S 01): S279-S311
DOI: 10.1055/s-0043-122301

Referat

Das Mikrobiom – die unplanbare Größe zukünftiger Therapien

Article in several languages: deutsch | English

Achim G. Beule

¹HNO-Uniklinik Münster

²Klinik und Poliklinik für Hals-Nasen-Ohrenkrankheiten der Universitätsmedizin Greifswald

› Author Affiliations

Abstract

Zusammenfassung

Unter Mikrobiom versteht man die Gesamtheit der bakteriellen, parasitären, viralen oder anderen zellulären Mikroorganismen, die den menschlichen Körper oder ein anderes Lebewesen besiedeln. Das Mikrobiom zeigt in den anatomischen Bereichen der Hals-Nasen-Ohrenheilkunde eine deutliche regionale Varianz. Für die Bereiche von Ohr, Nase, Rachen, Larynx und Haut sind jeweils verschiedene Interaktionen des Mikrobiomes mit allgemeinen Faktoren wie Alter, Diät und Lebensstilfaktoren (z. B. Rauchen) in den letzten Jahren bekannt geworden. Zudem liegen eine Reihe von Erkenntnissen vor, dass das Mikrobiom an der Pathogenese verschiedener Erkrankungen auch im HNO-Bereich beteiligt ist. Der vorgestellte Übersichtsartikel fasst die wesentlichen Erkenntnisse dieses sich aktuell äußerst rasch entwickelnden Forschungsgebietes überblickartig zusammen.

Schlüsselwörter

Mikrobiom - Sinusitis - Kopf-Hals-Tumoren - Otitis

Full Text

References

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