Chinesische Arzneimitteltherapie als mögliche Alternative zur Antibiotikatherapie

Summary

Phytotherapeutika bieten großes Potenzial zur Lösung des Problems multiresistenter Keime beizutragen. Die Chinesische Arzneimitteltherapie hat u.a. während der SARS-Epidemie wieder an Ansehen gewonnen, da sie als besonders wirksam erfahren wurde und intensiv erforscht wird. Aufgrund der Biodiversität Chinas existieren zahlreiche arzneilich nutzbare Arten. Die Chinesische Arzneimitteltherapie nutzt nicht nur einen Bestandteil, sondern auch Kombinationen von 2 bis zu 15 Pflanzen, um die Wirksamkeit durch Synergismen zu verstärken und Nebeneffekte zu reduzieren.

Der Beitrag stellt bewährte Rezepturen vor für häufig auftretende bakterielle Infekte sowie wichtige Studienergebnisse zu MRSA, Helicobacter pylori, Salmonellen und Harnwegsinfekten.

Keywords

Chinesische Arzneitherapie - CAT - Antibiotikaresistenz - Gentiana - Coptis - Dekokt

• Literatur

• 1 Luxenburger H, Hummelsberger J. Aintibiotikaresistenz im Fokus der EU-Gesundheitspolitik. DZA 2016; 59 (04) 41-43
• 2 Pharamacopoeia of the PR of China, Vol I. Beijing: People's Medical Publishing House; 2005
• 3 Porkert M. Theoretische Grundlagen der Chinesischen Medizin. Dinkelscherben: Phainon; 1991. 3
• 4 Unschuld PU, Pen Tsao. 2000. Jahre traditionelle pharmazeutische Literatur Chinas. München: Moos; 1973
• 5 Scheid V, Bensky D, Ellis A, Barolet R. Formulas & Strageties. Seattle: Eastland Press; 2009. 2
• 6 https://www.lfl.bayern.de/ipz/heilpflanzen/059214/index.php
• 7 Hu XY, Wu RH, Logue M. et al. Andrographis paniculata for symptonatic relief of acute respiratory tract infections in adults and children. A systematic review and meta-analysis. PLos One 2017; 12 (08) e0181780
• 8 Wang CY, Bai XY, Wang CH. Traditional Chinese medicine: a treasured natural resource of anticancer drug research and development. Am J Chin Med 2014; 42: 543-559
• 9 Huang J, Su D, Feng Y. et al. Antiviral herbs – present and future. Infect Disord Drug Targets 2014; 14: 61-73
• 10 Andújar I, Ríos JL, Giner RM. et al. Pharmacological properties of shikonin – a review of literature since 2002. Planta Medica 2013; 79: 1685-1697
• 11 Zhou YX, Xin HL, Rahman K. et al. Portulaca oleracea L.: a review of phytochemistry and pharmacological effects. BioMed Research International 2015; 925631
• 12 He JM, Mu Q. The medicinal uses of the genus Mahonia in traditional Chinese medicine: An ethnopharmacological, phytochemical and pharmacological review. J Ethnopharmacol 2015; 175: 668-683
• 13 Hao BJ, Wu YH, Wang JG. et al. Hepatoprotective and antiviral properties of isochlorogenic acid A from Laggera alata against hepatitis B virus infection. J Ethnopharmacol 2012; 144: 190-194
• 14 Wang YS, Wen ZQ, Li BT. et al. Ethnobotany, phytochemistry, and pharmacology of the genus Litsea: An update. J Ethnopharmacol 2016; 181: 66-107
• 15 Wells TN. Prevention and treatment of viral respiratory infections by traditional Chinese herbs?. Malaria Journal 2011; 10 S1 S3
• 16 Tong Y, Jing Y, Zhao D. et al. Fluoroquinolone-resistant uncomplicated urinary tract infections, Chinese herbal medicine may provide help. African Journal of Traditional, Complementary and Alternative medicines 2011; 8: 108-114
• 17 Zhang XG, Li GX, Zhao SS. et al. A review of dihydroartemisinin as another gift from traditional Chinese medicine not only for malaria control but also for schistosomiasis control. Parasitology Res 2014; 113: 1769-1773
• 18 Huang YQ, Huang GR, Wu MH. et al. Inhibitory effects of emodin, baicalin, schizandrin and berberine on hefA gene: treatment of Helicobacter pylori-induced multidrug resistance. World J Gastroenterol 2015; 21: 4225-4231
• 19 Tong Y, Jia S, Han B. Chinese herb-resistant clinical isolates of Escherichia coli. J Altern Complement Med 2013; 19: 387-388
• 20 Chang SS, Huang HJ, Chen CY. Two birds with one stone? Possible dual-targeting H1N1 inhibitors from traditional Chinese medicine. PLOS Computational Biology 2011; 7: e1002315
• 21 Liu X, Han Y, Peng K. et al. Effect of traditional Chinese medicinal herbs on Candida spp. from patients with HIV / AIDS. Adv Dent Res 2011; 23: 56-60
• 22 Chu Y, Liu H. Advances of research on anti-HIV agents from traditional Chinese herbs. Adv Dent Res 2011; 23: 67-75
• 23 Cui X, Wang Y, Kokudo N. et al. Traditional Chinese medicine and related active compounds against hepatitis B virus infection. BioScienceTrends 2010; 4: 39-47
• 24 Kwon HA, Kwon YJ, Kwon DY. et al. Evaluation of antibacterial effects of a combination of Coptidis Rhizoma, Mume Fructus, and Schizandrae Fructus against Salmonella. Int J Food Microbiol 2008; 127: 180-183
• 25 Muluye RA, Bian Y, Alemu PN. Anti-inflammatory and antimicrobial effects of heat-clearing Chinese herbs. J Tradit Complement Med 2014; 4: 93-98
• 26 Li T, Peng T. Traditional Chinese herbal medicine as a source of molecules with antiviral activity. Antiviral Research 2013; 97: 1-9
• 27 Zhang L, Wang G, Hou W. et al. Contemporary clinical research of traditional Chinese medicines for chronic hepatitis B in China. Hepatology 2010; 51: 690-698
• 28 Wang X, Jia W, Zhao A. et al. Anti-influenza agents from plants and traditional Chinese medicine. Phytother Res 2006; 20: 335-341
• 29 Yu YY, Wang H, Zhang SW. et al. Inhibition of methicillin-resistant Staphylococcus aureus by the compound Qingre granules. Chinese Medical Journal 2010; 123: 1017-1020
• 30 Flower A, Wang LQ, Lewith G. et al. Chinese herbal medicine for treating recurrent urinary tract infections in women. The Cochrane Database of Systematic Reviews 2015; 6: CD010446
• 31 Chen JK, Chen TT. Chinese Medical Herbology and Pharmacology. Art of Medicine Press; 2003
• 32 Huang YQ, Huang GR, Wu MH. et al. Inhibitory effects of emodin, baicalin, schizandrin and berberine on hefA gene: treatment of Helicobacter pylori-induced multidrug resistance. World J Gastroenterol 2015; 21 (14) 4225-423