PDF herunterladen
Ernährung & Medizin 2018; 33(01): 29-34
DOI: 10.1055/s-0043-124127
Wissen
© Haug Verlag in Georg Thieme Verlag KG Stuttgart · New York

Einfluss eines Synbiotikums auf den Gewichtsverlauf

Studie zur Modulation der Bacteroidetes-Firmicutes-Ratio
Michaela Axt-Gadermann
,
Victoria Lorenz
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
26. Februar 2018 (online)

Auch verfügbar auf
    Lizenzen und Reprints

Zusammenfassung

Aktuelle Untersuchungen belegen die Bedeutung des intestinalen Mikrobioms für die menschliche Gesundheit. Eine Dysbiose hat nicht nur lokale Auswirkungen im Darm, sondern kann den gesamten Organismus betreffen und verschiedene Stoffwechselstörungen begünstigen. Wird die Zusammensetzung des Mikrobioms durch Pro- und Präbiotika positiv verändert, kann sich dies u. a. auch in einem verringerten Körpergewicht zeigen.

 

  • Literatur

  • 1 Baeckhed F. Programming of host metabolism by the gut microbiota. Ann Nutr Metab 2011; 58 (Suppl. 02) 44-52
    CrossrefPubMedSuche in Google Scholar
  • 2 Baeckhed F, Ding H, Wang T. et al. The gut microbiota as an environmental factor that regulates fat storage. PNAS 2004; 101: 15718-15723
    CrossrefPubMedSuche in Google Scholar
  • 3 Allin KH, Nielsen T, Pedersen O. Mechanisms in endocrinology: Gut microbiota in patients with type 2 diabetes mellitus. Eur J Endocrinol 2015; 172: R167-177
    CrossrefPubMedSuche in Google Scholar
  • 4 Robles Alonso V, Guarner F. Linking the gut microbiota to human health. Br J Nutr 2013; 109 (Suppl. 02) S21-26
    CrossrefPubMedSuche in Google Scholar
  • 5 Turnbaugh PJ, Ley RE, Hamady M. The human microbiome project. Nature 2007; 449: 804-810
    CrossrefPubMedSuche in Google Scholar
  • 6 Ley RE, Turnbaugh PJ, Klein S. et al. Microbial ecology: human gut microbes associated with obesity. Nature 2006; 444: 1022-1023
    CrossrefPubMedSuche in Google Scholar
  • 7 Jumpertz R, Le DS, Turnbaugh PJ. et al. Energybalance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans. Am J Clin Nutr 2011; 94: 58-65
    CrossrefPubMedSuche in Google Scholar
  • 8 Alang N, Kelly CR. Weight gain after fecal microbiota transplantation. Open Forum Infect Dis. 2015 doi:10.1093/ofid/ofv004
    PubMedSuche in Google Scholar
  • 9 Kostic AD, Gevers D, Siljander H. et al. The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes. Cell Host & Microbe 2015; 17: 260-273
    CrossrefPubMedSuche in Google Scholar
  • 10 Abrahamsson TR, Jakobsson HE, Andersson AF. et al. Low diversity of gut microbiota in infants with atopic eczema. J Allergy Clin Immunol 2012; 129: 434-440
    CrossrefPubMedSuche in Google Scholar
  • 11 Candela M, Rampelli S, Turroni S. et al. Unbalance of intestinal microbiota in atopic children. BMC Microbiology 2012; 12: 95
    CrossrefPubMedSuche in Google Scholar
  • 12 Santacruz A, Collado MC, García-Valdés L. Gut microbiota composition is associated with body weight, weight gain, and biochemical parameters in pregnant women. Br J Nutr 2010; 104: 83-92
    CrossrefPubMedSuche in Google Scholar
  • 13 Trasande L, Blustein J, Liu M. Infant antibiotic exposures and early-life body mass. Int J Obes (Lond) 2013; 37: 16-23
    CrossrefPubMedSuche in Google Scholar
  • 14 Thuny F, Richet H, Casalta JP. et al. Vancomycin treatment of infective endocarditis is linked with recently acquired obesity. PLoS One 2010; 5: e9074
    CrossrefPubMedSuche in Google Scholar
  • 15 Genta S, Cabrera W, Habib N. et al. Yacon syrup: beneficial effects on obesity and insulin resistance in humans. Clin Nutr 2009; 28: 182-187
    CrossrefPubMedSuche in Google Scholar
  • 16 Parnell JA, Reimer RA. Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults. Am J Clin Nutr 2009; 89: 1751-1759
    CrossrefPubMedSuche in Google Scholar
  • 17 Guerin-Deremaux L, Pochat M, Reifer C. et al. Dose-response impact of a soluble fiber, NUTRIOSE®, on energy intake, body weight and body fat in humans. Global Epidemic Obesity 2013; 1: 2
    CrossrefPubMedSuche in Google Scholar
  • 18 Kadooka Y, Sato M, Imaizumi K. Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial. Eur J Clin Nutr 2010; 64: 636-643
    CrossrefPubMedSuche in Google Scholar
  • 19 Sanchez M, Darimont C, Drapeau V.. et al. Effect of Lactobacillus rhamnosus CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women. Br J Nutr 2014; 111: 1507-1519
    CrossrefPubMedSuche in Google Scholar
  • 20 Bjerg AT, Sørensen MB, Krych L. et al. The effect of Lactobacillus paracasei subsp. paracasei L. casei W8® on blood levels of triacylglycerol is independent of colonisation. Benef Microbes 2015; 6: 263-269
    CrossrefPubMedSuche in Google Scholar
  • 21 Bjerg AT, Kristensen M, Ritz Ch. et al. Lactobacillus paracasei subsp paracasei L. casei W8 suppresses energy intake acutely. Appetite 2014; 82: 111-118
    CrossrefPubMedSuche in Google Scholar
  • 22 Ahmadi S, Jamilian M, Tajabadi-Ebrahimi M. et al. The effects of synbiotic supplementation on markers of insulin metabolism and lipid profiles in gestational diabetes: A randomised, double-blind, placebo-controlled trial. Br J Nutr 2016; 116: 1394-1401
    CrossrefPubMedSuche in Google Scholar
  • 23 Chang YS, Trivedi MK, Jha A. et al. Synbiotics for prevention and treatment of atopic dermatitis: a meta-analysis of randomized clinical trials. JAMA Pediatr 2016; 170: 236-242
    CrossrefPubMedSuche in Google Scholar
  • 24 Schlichte MJ, Vandersall A, Katta R. Diet and eczema: a review of dietary supplements for the treatment of atopic dermatitis. Dermatol Pract Concept 2016; 6: 23-29
    PubMedSuche in Google Scholar