Abstract
Rosai-Dorfman-Destombes (RDD) disease is also known as sinus histiocytosis with massive
lymphadenopathy. It is an uncommon heterogeneous disease of children and young adults.
Most of the patients with RDD generally present with painless lymphadenopathy, while
extranodal and multisystem manifestation of the disease is unusual. The diagnosis
is based on the imaging with clinicopathological correlation. Flourine-18 fluorodeoxyglucose
positron emission tomography/computed tomography is useful for the initial staging
of the RDD lesions, which have similar appearance and avidity like intermediate and
high-grade lymphomas. Here, we present the case of a 55-year-old female presented
with left breast mass that turned out to be the extranodal Rosai-Dorfman disease.
Keywords
18F-FDG PET/CT - breast - histopathology - mammogram - Rosai-Dorfman disease - ultrasound
