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CC BY 4.0 · Rev Bras Ginecol Obstet 2023; 45(01): 049-054
DOI: 10.1055/s-0043-1763495
Febrasgo Position Statement

Prediction and prevention of preeclampsia

Number 1 – January 2023
Fernando Maia Peixoto-Filho 
1   Universidade Federal Fluminese, Niteroi, RJ, Brazil
,
Fabricio da Silva Costa 
2   Maternal Fetal Medicine Unit, Gold Coast University Hospital, Southport, Queensland, Australia
,
Sergio Kobayashi 
3   Universidade Federal de São Paulo, São Paulo, SP, Brazil
,
Patricia El Beitune 
4   Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil
,
Adriana Gualda Garrido 
5   Universidade de Brasília, Brasília, DF, Brazil
,
Anselmo Verlangieri Carmo 
6   Universidade Federal de Mato Grosso, Cuiabá, MT, Brazil
,
Guilherme de Castro Rezende 
7   Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
,
Heron Werner Junior 
8   Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
,
Joffre Amin Junior 
9   Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
,
Jorge Roberto Di Tommaso Leão 
10   Universidade do Estado do Amazonas, Manaus, AM, Brazil
,
Luciano Marcondes Machado Nardozza 
11   Universidade Federal de São Paulo, São Paulo, SP, Brazil
,
Luiz Eduardo Machado 
12   Escola Bahiana de Medicina e Saúde Pública, Salvador, BA, Brazil
,
Manoel Alfredo Curvelo Sarno 
13   Universidade Federal da Bahia, Salvador, BA, Brazil
,
Pedro Pires Ferreira Neto 
14   Universidade de Pernambuco, Recife, PE, Brazil
,
Eduardo Becker Júnior 
15   Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil
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Keypoints

  • Preeclampsia (PE) is an important cause of maternal and perinatal mortality worldwide, accounts for 10% to 15% of direct maternal deaths, and 99% of these deaths are in low-income countries.

  • Preeclampsia is defined as systolic blood pressure of ≥140 mmHg and/or diastolic blood pressure of ≥90 mmHg on at least two occasions, measured four hours apart in previously normotensive women, and is accompanied by one or more of the following new-onset conditions after 20 weeks' gestation: (1) proteinuria, (2) evidence of other maternal organ dysfunction, or (3) uteroplacental dysfunction.

  • Preeclampsia is classified into: (1) early PE (delivery < 34+0 weeks' gestation); (2) preterm PE (delivery < 37+0 weeks' gestation); (3) late-onset PE (delivery ≥ 34+0 weeks' gestation); (4) term PE (delivery ≥ 37+0 weeks' gestation).

  • In Brazil, the incidence of PE varies from 1.5% to 7%; of preterm PE is 2% and of eclampsia is 0.6%. However, these statistics are likely to be underestimated and vary according to the region studied.

  • Screening strategies for PE vary depending on the parameters used, pre-test risk, outcome stratification, and the gestational age at which screening is performed. However, there is consensus in the literature that no single-parameter screening test has been shown to adjust the preexisting maternal risk for PE with sufficient specificity and sensitivity for clinical use.

The National Specialized Commission on Ultrasonography in GO of the Brazilian Federation of Gynecology and Obstetrics Associations (Febrasgo) endorses this document. The production of content is based on scientific evidence on the proposed theme and the results presented contribute to clinical practice.




Publication History

Article published online:
06 March 2023

© 2023. Federação Brasileira de Ginecologia e Obstetrícia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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