Synthesis, Inhaltsverzeichnis Synthesis 2024; 56(14): 2277-2283DOI: 10.1055/s-0043-1763690 paper One-Pot N-α-C(sp3)–H Bond Functionalisation Cascade for the Synthesis of Polysubstituted Imidazoles Vikas D. Kadu ∗ a School of Chemical Sciences, Punyashlok Ahilyadevi Holkar Solapur University, Solapur 413255, Maharashtra, India , Naga Chandradudu Sankala b Department of Chemistry, College of Engineering, Rayalseema University, Kurnool 518002, Andhra Pradesh, India , Mahesh G. Hublikar a School of Chemical Sciences, Punyashlok Ahilyadevi Holkar Solapur University, Solapur 413255, Maharashtra, India , Shahaji I. Bansode a School of Chemical Sciences, Punyashlok Ahilyadevi Holkar Solapur University, Solapur 413255, Maharashtra, India , Raghunath B. Bhosale a School of Chemical Sciences, Punyashlok Ahilyadevi Holkar Solapur University, Solapur 413255, Maharashtra, India › Institutsangaben Artikel empfehlen Abstract Artikel einzeln kaufen Alle Artikel dieser Rubrik Abstract A one-pot eco-friendly oxidative N-α-C(sp3)–H bond functionalisation of arylmethylamines for the synthesis of tetrasubstituted imidazoles is demonstrated. The substrate scope of these amines has been well-explored with different substrates, such as 1,2-diketones, an α-hydroxy ketone and phenylacetophenone. In the presence of FeCl3 catalyst and green oxidant O2, the easily accessible substrates afforded tetrasubstituted imidazoles in up to 94% yield. Key words Key wordsimidazoles - iron catalysis - oxidative coupling - N-α-C(sp3)–H functionalisation - one-pot reaction Volltext Referenzen References 1 Kabi AK, Sravani S, Gujjarappa R, Garg A, Vodnala N, Tyagi U, Kaldhi D, Velayutham R, Gupta S, Malakar CC. In Nanostructured Biomaterials. 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