Endoscopy 2023; 55(S 02): S64-S65
DOI: 10.1055/s-0043-1765155
Abstracts | ESGE Days 2023
Oral presentation
Optimizing bowel cleansing in colonoscopy 21/04/2023, 11:30 – 12:30 Liffey Meeting Room 1

Restrictive diets are not necessary with current bowel cleansing standards. Results of a non-inferiority clinical trial

S. Machlab
1   Hospital Parc Taulí de Sabadell, Sabadell, Spain
2   Facultat de Medicina – UAB, Bellaterra, Spain
,
P. Ruiz-Ramirez
3   Hospital Universitari MútuaTerrassa, Terrassa, Spain
,
B. Gomez
4   Hospital de Mataró, Mataró, Spain
,
P. Lopez
1   Hospital Parc Taulí de Sabadell, Sabadell, Spain
,
A. Gimeno-Garcia
5   Hospital Universitario de Canarias, La Laguna, Spain
,
M. Pujals
3   Hospital Universitari MútuaTerrassa, Terrassa, Spain
,
S. Tanco
4   Hospital de Mataró, Mataró, Spain
,
L. Sargatal
6   Terrassa Hospital, Terrassa, Spain
,
B. Perez
5   Hospital Universitario de Canarias, La Laguna, Spain
,
R. Justicia
6   Terrassa Hospital, Terrassa, Spain
,
F. Fernandez-Bañares
3   Hospital Universitari MútuaTerrassa, Terrassa, Spain
,
O. Valero
7   UAB Servei d'Estadística Aplicada, Cerdanyola del Vallès, Spain
,
R. Campo
1   Hospital Parc Taulí de Sabadell, Sabadell, Spain
2   Facultat de Medicina – UAB, Bellaterra, Spain
,
E. Martinez-Bauer
1   Hospital Parc Taulí de Sabadell, Sabadell, Spain
2   Facultat de Medicina – UAB, Bellaterra, Spain
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Aims To evaluate the impact of restrictive diet within modern standards of preparation for colonoscopy.

Methods We conducted a multicenter, randomized, parallel group, non-inferiority clinical trial. Population screening program FIT+ subjects were included. All followed a split-dose preparation with PEG+Asc 1L for morning colonoscopy. Bisacodyl was added in case of risk of inadequate preparation. Individuals were randomized to follow a 1-day low-residue diet (LRD) or free diet without restrictions (FD). A 5% non-inferiority margin was established. Bowel cleansing was assessed according to the Boston scale. In addition, diet and evacuating solution tolerability, perceived quality of the instructions and efficiency variables of colonoscopy were assessed ([Fig. 1]).

Zoom Image
Fig. 1

Results 278 individuals assigned to FD and 275 to LRD were analyzed. Both groups were homogeneous with no significant differences between them. Risk of poor preparation was similar (FD 13.6% and 14.7% LRD, p=0.7). Adherence to PEG+Asc 1L was similar. There were no differences in terms of tolerability (67.8% vs. 67.9%) or in the instructions (95.7% vs. 96.7%). FD was better tolerated (94.7% vs. 83.2% p < 0.001). Adequate preparations rate were 96.4% vs. 97.8% (ẟ=1.4%, p=0.3). There were no differences in withdrawal times or in the adenoma detection rate. In the multivariate analysis, the diet had no influence on preparation quality.

Conclusions It is not necessary to restrict the diet following the current standards of preparation for colonoscopy [1] [2] [3].



Publication History

Article published online:
14 April 2023

© 2023. European Society of Gastrointestinal Endoscopy. All rights reserved.

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