Endoscopy 2023; 55(S 02): S66
DOI: 10.1055/s-0043-1765158
Abstracts | ESGE Days 2023
Oral presentation
Optimizing bowel cleansing in colonoscopy 21/04/2023, 11:30 – 12:30 Liffey Meeting Room 1

Screening colonoscopy in individuals under 50 years of age: a Greek population-based prospective study

I. Braimakis
1   Army Share Fund Hospital (NIMTS), Gastroenterology Clinic, Athens, Greece
,
I. Stasinos
1   Army Share Fund Hospital (NIMTS), Gastroenterology Clinic, Athens, Greece
,
C. Poutakidis
1   Army Share Fund Hospital (NIMTS), Gastroenterology Clinic, Athens, Greece
,
S. Gongaki
1   Army Share Fund Hospital (NIMTS), Gastroenterology Clinic, Athens, Greece
,
O. Sidiropoulos
1   Army Share Fund Hospital (NIMTS), Gastroenterology Clinic, Athens, Greece
,
P. S. Zantza
1   Army Share Fund Hospital (NIMTS), Gastroenterology Clinic, Athens, Greece
,
K. Toumpelis
1   Army Share Fund Hospital (NIMTS), Gastroenterology Clinic, Athens, Greece
,
A. Theofanopoulou
1   Army Share Fund Hospital (NIMTS), Gastroenterology Clinic, Athens, Greece
,
C. Kalantzis
1   Army Share Fund Hospital (NIMTS), Gastroenterology Clinic, Athens, Greece
,
P. Tsibouris
1   Army Share Fund Hospital (NIMTS), Gastroenterology Clinic, Athens, Greece
,
P. Apostolopoulos
1   Army Share Fund Hospital (NIMTS), Gastroenterology Clinic, Athens, Greece
› Author Affiliations
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Aims The aim of this study is to assess the risk for colorectal neoplasia in Greek individuals under 50 years, which is the currently recommended age for colorectal cancer (CRC) screening colonoscopy onset in average risk populations [1].

Methods This is a prospective study of average CRC risk individuals (no family history or symptoms indicating CRC) aged 45-49 years old that underwent colonoscopy in the Gastroenterology Department of Army Share Fund Hospital during a 9-month period. Exclusion criteria comprised colorectal surgery, IBD and hereditary CRC syndromes. A population of 50-55 years old undergoing screening colonoscopy during the same period was used as our control group. All identified polyps were categorized according to size and histopathological results.

Results Out of 268 participants in our study, 63 persons 45-49 years old formed the study group and 205 persons 50-55 years old formed the control group. Polyp Detection Rate (PDR) and Adenoma Detection Rate (ADR) corresponded to 33,3% and 20,6% in the study group versus 40,1% and 20,9% in the control group, respectively. Moreover, CRC was detected with a rate of 3,2% in the study group versus 1,5% in the control group. No statistically significant difference was noted between the 2 groups in terms of PDR, ADR and CRC rates as well as in terms of size.

Conclusions In the present study population, we detected similar risk for colorectal neoplasia and CRC in both age groups. This observation adds to recent findings of other studies concerning the commencement of CRC screening in individuals younger than 50 years of age.1



Publication History

Article published online:
14 April 2023

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  • 1 Patel SG, May FP, Anderson JC. et al. Updates on Age to Start and Stop Colorectal Cancer Screening: Recommendations From the U.S. Multi-Society Task Force on Colorectal Cancer [published correction appears in Gastroenterology. 2022 Jul;163(1):339]. Gastroenterology 2022; 162 (01) 285-299
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