Open Access
CC BY-NC-ND 4.0 · Ann Natl Acad Med Sci 2023; 59(04): 196-201
DOI: 10.1055/s-0043-1768138
Original Article

Measurement of Intact Serum Parathormone and Corrected Serum Calcium after Thyroid Surgery

Sweety Kumari
1   Department of Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
,
Rahul Khanna
1   Department of Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
,
Neeraj K. Agrawal
2   Department of Endocrinology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
,
Ritika Khanna
3   Dermatology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
,
Ram Niwas Meena
1   Department of Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
› Institutsangaben
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Abstract

Postoperative hypocalcemia is an important complication of thyroid surgery. The present study was undertaken to measure the serum levels of intact parathormone (iPTH) and corrected serum calcium (CSC) in the immediate postoperative period and then sequentially till 1 month after thyroid surgery. A total of 36 patients undergoing total thyroidectomy and 44 undergoing hemithyroidectomy had measurement of the level of iPTH and CSC at 1 hour, 1 day, 1 week, and 1 month after surgery. A mean drop of 9.3% in CSC, 40% in iPTH, and 10% in ionic calcium levels was noted 1 hour after total thyroidectomy. All the patients recovered to near preoperative levels at the 1-month follow-up. Among hemithyroidectomy patients, significant postsurgery drop in levels was not observed. The importance of the study is early recognition of a hypoparathyroid state at 1 hour after surgery and institution of calcium replacement, thereby sparing the patient from unpleasant symptoms of hypocalcemia. Furthermore, patients with a drop in the iPTH levels below the defined hypoparathyroidism levels should have careful evaluation of their thyroidectomy specimen for identification and possible autotransplantation of the parathyroid gland intraoperatively or in the immediate postoperative time frame.

Ethical Approval Statement

The study was a part of MS (surgery) thesis protocol of Dr. Sweety Kumari and was duly approved by the institutional ethics committee and the PG medical board.




Publikationsverlauf

Artikel online veröffentlicht:
27. November 2023

© 2023. National Academy of Medical Sciences (India). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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