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CC BY 4.0 · Arq Neuropsiquiatr 2023; 81(04): 334-339
DOI: 10.1055/s-0043-1768157
Original Article

Analysis of risk factors associated with cerebral angiography headache

Análise de fatores de risco associados a cefaleia da angiografia cerebral
Tiago Madeira 
1   Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, São Paulo SP, Brazil.
2   Hospital Santa Rita de Cássia, Departamento de Neurologia e Neurocirurgia, Vitória ES, Brazil.
,
Amanda Viguini Tolentino Correa 
2   Hospital Santa Rita de Cássia, Departamento de Neurologia e Neurocirurgia, Vitória ES, Brazil.
,
Gabriela de Paula Abranches 
2   Hospital Santa Rita de Cássia, Departamento de Neurologia e Neurocirurgia, Vitória ES, Brazil.
,
Marcelo Rodrigues Masruha 
1   Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, São Paulo SP, Brazil.
› Institutsangaben Support The present study was financed in part by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES, in the Portuguese acronym) – Finance Code 001.
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Abstract

Background Despite previous studies indicating a moderate/high incidence of angiography headache (AH), there is still limited data about the risk factors associated with its occurrence.

Objective The present study aimed to assess the associations among demographic, clinical, and technical characteristics of cerebral digital subtraction angiography (DSA) and the occurrence of AH.

Methods Cross-sectional analytical observational study with a sample comprised of individuals with a recommendation for elective DSA. Clinical interviews were conducted to assess the occurrence of AH, using a standardized questionnaire.

Results Among 114 subjects, the mean age was 52.8 (±13.8) years old, 75.4% (86/114) were women, 29.8% (34/114) had a history of migraines, and 10.5% (12/114) had chronic headaches. The overall frequency of AH was 45.6% (52/114). Of those, 88.4% (46/52) underwent 3D angiography, 7.7% (4/52) underwent aortography, and 1.9% (1/52) underwent both procedures. There was a statistically significant association between AH and previous history of migraine (odds ratio [OR]: 4.9; 95% confidence interval [CI] 1.62–14.7; p = 0.005) and 3D angiography (OR 6.62; 95%CI: 2.04–21.5; p = 0.002).

Conclusions 3D angiography is strongly associated with the occurrence of AH, which has never been reported before. The association between a previous history of migraine and AH confirms the results of previous studies.

Resumo

Antecedentes Apesar de estudos prévios indicarem uma incidência moderada/alta de cefaleia da angiografia (CA), os dados sobre os fatores de risco associados à sua ocorrência ainda são relativamente escassos.

Objetivo O presente estudo teve como objetivo avaliar as associações entre as características demográficas, clínicas e técnicas da angiografia cerebral por subtração digital (ACSD) e a ocorrência de CA.

Métodos Estudo observacional analítico transversal com uma amostra composta por indivíduos com indicação de ACSD em caráter eletivo. Entrevistas clínicas foram realizadas utilizando um questionário padronizado para acessar a ocorrência de CA.

Resultados Entre os 114 indivíduos, a idade média foi de 52,8 (±13,8) anos, 75,4% (86/114) eram mulheres, 29,8% (34/114) tinham histórico de enxaqueca e 10,5% (12/114) tinham cefaleia crônica. A frequência geral de CA foi de 45,6% (52/114). Desses, 88,4% (46/52) foram submetidos à angiografia 3D, 7,7% (4/52), à aortografia e 1,9% (1/52), aos dois procedimentos. Houve associação estatisticamente significativa entre CA e histórico prévio de enxaqueca (odds ratio [OR] 4,9; intervalo de confiança [IC] 95%: 1,62–14,7; p = 0,005) e angiografia 3D (OR 6,62; IC95%: 2,04–21,5; p = 0,002).

Conclusões A angiografia 3D está fortemente associada à ocorrência de CA, o que é inédito na literatura. A associação entre um histórico de enxaqueca e a CA confirma os resultados de estudos anteriores.

Keywords

Cerebral Angiography - Headache - Migraine Disorders - Headache Disorders, Secondary - Headache Disorders

Palavras-chave

Angiografia Cerebral - Cefaleia - Transtornos de Enxaqueca - Cefaleias Secundárias - Transtornos da Cefaleia

Authors' Contributions

TM: data curation, funding acquisition, investigation, methodology, writing – original draft, writing – review & editing; AVTC, GPA: writing – review & editing; MMR: conceptualization, data curation, project administration, writing – original draft, writing – review & editing.




Publikationsverlauf

Eingereicht: 18. Oktober 2022

Angenommen: 18. Januar 2023

Artikel online veröffentlicht:
09. Mai 2023

© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)

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  • References

  • 1 Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders. 3rd edition. Cephalalgia. 2018;38(1):1–211.
  • 2 Gil-Gouveia R, Fernandes Sousa R, Lopes L, Campos J, Pavão Martins I. Headaches during angiography and endovascular procedures. J Neurol 2007; 254 (05) 591-596
    CrossrefPubMedSuche in Google Scholar
  • 3 Gil-Gouveia RS, Sousa RF, Lopes L, Campos J, Martins IP. Post-angiography headaches. J Headache Pain 2008; 9 (05) 327-330
    CrossrefPubMedSuche in Google Scholar
  • 4 Kwon MA, Hong CK, Joo JY, Kim YB, Chung J. Headache After Cerebral Angiography: Frequency, Predisposing Factors, and Predictors of Recovery. J Neuroimaging 2016; 26 (01) 89-94
    CrossrefPubMedSuche in Google Scholar
  • 5 Ramadan NM, Gilkey SJ, Mitchell M, Sawaya KL, Mitsias P. Postangiography headache. Headache 1995; 35 (01) 21-24
    CrossrefPubMedSuche in Google Scholar
  • 6 Demir T, Onan HB, Balal M, Aksungur E, Bicakci S. Clinical features and risk factors of angiography headache and evaluation of its relationship to primary headaches. Neurol Neurochir Pol 2019; 53 (06) 442-448
    CrossrefPubMedSuche in Google Scholar
  • 7 Aktan Ç, Özgür Ö, Sindel T, Dora B. Characteristics of headache during and after digital substraction angiography: A critical re-appraisal of the ICHD-3 criteria. Cephalalgia 2017; 37 (11) 1074-1081
    CrossrefPubMedSuche in Google Scholar
  • 8 Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand 1983; 67 (06) 361-370
    Suche in Google Scholar
  • 9 Ajiboye N, Chalouhi N, Starke RM, Zanaty M, Bell R. Unruptured Cerebral Aneurysms: Evaluation and Management. ScientificWorldJournal 2015; 2015: 954954
    CrossrefPubMedSuche in Google Scholar
  • 10 Bair MJ, Robinson RL, Katon W, Kroenke K. Depression and pain comorbidity: a literature review. Arch Intern Med 2003; 163 (20) 2433-2445
    CrossrefPubMedSuche in Google Scholar
  • 11 Martins IP, Baeta E, Paiva T, Campos J, Gomes L. Headaches during intracranial endovascular procedures: a possible model of vascular headache. Headache 1993; 33 (05) 227-233
    CrossrefPubMedSuche in Google Scholar
  • 12 Kremer S, Grand S, Dananchet Y. et al. MRI during postangiography headache. Neurology 2002; 58 (09) 1425
    CrossrefPubMedSuche in Google Scholar