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CC BY 4.0 · World J Nucl Med
DOI: 10.1055/s-0043-1768447
Case Series

Thyroid Cartilage Metastases from Prostate Cancer on 18F PSMA PET CT: A Case Series

Poonamjeet Loyal
1   Department of Radiology, Aga Khan University Hospital, Nairobi, Kenya
,
Samuel Gitau
2   PET/CT Imaging, Department of Radiology, Aga Khan University Hospital, Nairobi, Kenya
,
Khalid Makhdomi 
3   Section of Nuclear Medicine, Department of Radiology, Aga Khan University Hospital, Nairobi, Kenya
› Author Affiliations Funding None.
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Abstract

Prostate cancer metastases to the thyroid cartilage is an extremely rare phenomenon. We report three cases of advanced prostate carcinoma with metastases to the thyroid cartilage identified on 18F prostate-specific membrane antigen-1007 (PSMA-1007) positron emission tomography (PET)/computed tomography (CT). The pathophysiology and possibility for under-reporting are also discussed. Prostate cancer metastases to the larynx should be considered in the differential diagnosis of thyroid cartilage lesions in patients with advanced prostate cancer and is associated with poor prognosis.

Keywords

thyroid cartilage - prostate cancer - metastases

Author Contribution

All the authors contributed to the content, design, literature search, manuscript preparation, manuscript editing, and manuscript review.


The manuscript has been read and approved by all the authors, and the requirements for authorship have been met, and each author believes that the manuscript represents honest work, if that information is not provided




Publication History

Article published online:
26 June 2024

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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  • References

  • 1 Rawla P. Epidemiology of prostate cancer. World J Oncol 2019; 10 (02) 63-89
    CrossrefPubMedGoogle Scholar
  • 2 Taitt HE. Global trends and prostate cancer: a review of incidence, detection, and mortality as influenced by race, ethnicity, and geographic location. Am J Men Health 2018; 12 (06) 1807-1823
    CrossrefPubMedGoogle Scholar
  • 3 Korir A, Okerosi N, Ronoh V, Mutuma G, Parkin M. Incidence of cancer in Nairobi, Kenya (2004-2008). Int J Cancer 2015; 137 (09) 2053-2059
    CrossrefPubMedGoogle Scholar
  • 4 Qureshi AM, Makhdomi K, Stones W. Prostate-specific antigen as a risk factor for skeletal metastasis in native ethnic African men with prostate cancer: a case-control study. World J Nucl Med 2017; 16 (01) 26-32
    Article in Thieme ConnectPubMedGoogle Scholar
  • 5 Barnes L. Metastases to the head and neck: an overview. Head Neck Pathol 2009; 3 (03) 217-224
    CrossrefPubMedGoogle Scholar
  • 6 Prescher A, Schick B, Stütz A, Brors D. Laryngeal prostatic cancer metastases: an underestimated route of metastases?. Laryngoscope 2002; 112 (8, Pt 1): 1467-1473
    CrossrefPubMedGoogle Scholar
  • 7 Gaber AM, Núñez R, Delpassand E. Cases of thyroid cartilage metastasis as abnormal findings seen in prostate cancer patients visualized by 68Ga-PSMA-11 PET/CT. Egypt J Radiol Nucl Med 2021; 52: 134
    CrossrefGoogle Scholar
  • 8 Tupalli A, Damle NA, Thankarajan AS. et al. An unusual case of simultaneous cricoid and thyroid cartilage metastases from prostatic adenocarcinoma on 68Ga-PSMA PET/CT. Nucl Med Mol Imaging 2020; 54 (01) 61-62
    CrossrefPubMedGoogle Scholar