Subscribe to RSS
DOI: 10.1055/s-0043-1768608
Techniques Providing Endpoints for Revascularization in Chronic Limb-Threatening Ischemia
Abstract
It is frequently difficult to estimate the revascularization endpoint in patients with chronic limb-threatening ischemia where there may be extensive multifocal multiarterial disease. There have been attempts to identify an endpoint for revascularization procedures, but none has become the standard of care. An ideal indicator of an endpoint can objectively quantify tissue perfusion, predict wound healing, and is easily and efficiently used intraprocedurally to assist real-time decision making on whether adequate perfusion has been reached. Candidate techniques to evaluate endpoints post-revascularization are discussed here.
Keywords
peripheral arterial disease - chronic limb-threatening ischemia - interventional radiology - angioplasty - stent - woundPublication History
Article published online:
16 June 2023
© 2023. Thieme. All rights reserved.
Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
-
References
- 1 The SAGE Group reports that in 2007 approximately 2.8 million people in Western Europe suffered from critical limb ischemia [press release]. Atlanta, GASAGE Group. October 20, 2008. Accessed April 13, 2023 at: https://thesagegroup.us/press%20releases/PressReleaseCLI%20W%20Eu08.html
- 2 Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FGR. On Behalf of the TASC II Working Group. Inter-society consensus for the management of peripheral arterial disease (TASC II). J Vasc Surg 2007; 45 (1, Suppl S): S5-S67
- 3 Jämsén TS, Manninen HI, Tulla HE, Jaakkola PA, Matsi PJ. Infrainguinal revascularization because of claudication: total long-term outcome of endovascular and surgical treatment. J Vasc Surg 2003; 37 (04) 808-815
- 4 Bryce Y, Katzen B, Patel P. et al. Closing the gaps in racial disparities in critical limb ischemia outcome and amputation rates: proceedings from a Society of Interventional Radiology Foundation Research Consensus Panel. J Vasc Interv Radiol 2022; 33 (05) 593-602
- 5 Mustapha JA, Saab FA, Martinsen BJ. et al. Digital subtraction angiography prior to an amputation for critical limb ischemia (CLI): an expert recommendation statement from the CLI Global Society to Optimize Limb Salvage. J Endovasc Ther 2020; 27 (04) 540-546
- 6 Jongsma H, Bekken JA, Akkersdijk GP, Hoeks SE, Verhagen HJ, Fioole B. Angiosome-directed revascularization in patients with critical limb ischemia. J Vasc Surg 2017; 65 (04) 1208-1219.e1
- 7 Bunt TJ, Holloway GA. TcPO2 as an accurate predictor of therapy in limb salvage. Ann Vasc Surg 1996; 10 (03) 224-227
- 8 Catella J, Long A, Mazzolai L. What is currently the role of TcPO2 in the choice of the amputation level of lower limbs? A comprehensive review. J Clin Med 2021; 10 (07) 1413
- 9 McPhail R, Cooper LT, Hodge DO, Cabanel ME, Rooke TW. Transcutaneous partial pressure of oxygen after surgical wounds. Vasc Med 2004; 9 (02) 125-127
- 10 Byrne P, Provan JL, Ameli FM, Jones DP. The use of transcutaneous oxygen tension measurements in the diagnosis of peripheral vascular insufficiency. Ann Surg 1984; 200 (02) 159-165
- 11 Kagadis GC, Tsantis S, Gatos I, Spiliopoulos S, Katsanos K, Karnabatidis D. 2D perfusion DSA with an open-source, semi-automated, color-coded software for the quantification of foot perfusion following infrapopliteal angioplasty: a feasibility study. Eur Radiol Exp 2020; 4 (01) 47
- 12 Accessed November 7, 2022 at: https://clinicaltrials.gov/ct2/show/NCT04356092
- 13 Duprée A, Rieß H, Detter C, Debus ES, Wipper SH. Utilization of indocyanine green fluorescent imaging (ICG-FI) for the assessment of microperfusion in vascular medicine. Innov Surg Sci 2018; 3 (03) 193-201
- 14 Settembre N, Kauhanen P, Albäck A, Spillerova K, Venermo M. Quality control of the foot revascularization using indocyanine green fluorescence imaging. World J Surg 2017; 41 (07) 1919-1926
- 15 Van den Hoven P, S Weller F, Van De Bent M. et al. Near-infrared fluorescence imaging with indocyanine green for quantification of changes in tissue perfusion following revascularization. Vascular 2022; 30 (05) 867-873
- 16 Senarathna J, Rege A, Li N, Thakor NV. Laser speckle contrast imaging: theory, instrumentation and applications. IEEE Rev Biomed Eng 2013; 6: 99-110
- 17 Sibley III RC, Reis SP, MacFarlane JJ, Reddick MA, Kalva SP, Sutphin PD. Noninvasive physiologic vascular studies: a guide to diagnosing peripheral arterial disease. Radiographics 2017; 37 (01) 346-357
- 18 Arkoudis NA, Katsanos K, Inchingolo R, Paraskevopoulos I, Mariappan M, Spiliopoulos S. Quantifying tissue perfusion after peripheral endovascular procedures: novel tissue perfusion endpoints to improve outcomes. World J Cardiol 2021; 13 (09) 381-398
- 19 Sommerset J, Mize A, Mebus P, Costantino M. Bringing the vascular lab inside the procedure room. Tech Vasc Interv Radiol 2022; 25 (04) 100861
- 20 Teso D, Sommerset J, Dally M, Feliciano B, Vea Y, Jones RK. Pedal acceleration time (PAT): a novel predictor of limb salvage. Ann Vasc Surg 2021; 75: 189-193