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J Pediatr Infect Dis 2023; 18(05): 266-271
DOI: 10.1055/s-0043-1769120
Case Report

Plastic Bronchitis and Human Bocavirus: A Report of Three Cases

Asli Imran Yilmaz 
1   Department of Pediatric Pulmonology, Meram Faculty of Medicine, Necmettin Erbakan University, Meram, Konya, Türkiye
,
Ahmet Çopur
2   Department of Pediatrics, Meram Faculty of Medicine, Necmettin Erbakan University, Meram, Konya, Türkiye
,
Havva Parlatan
2   Department of Pediatrics, Meram Faculty of Medicine, Necmettin Erbakan University, Meram, Konya, Türkiye
,
Hanife Tuğçe Çağlar 
1   Department of Pediatric Pulmonology, Meram Faculty of Medicine, Necmettin Erbakan University, Meram, Konya, Türkiye
,
Gökçen Ünal
1   Department of Pediatric Pulmonology, Meram Faculty of Medicine, Necmettin Erbakan University, Meram, Konya, Türkiye
,
Fatih Ercan 
1   Department of Pediatric Pulmonology, Meram Faculty of Medicine, Necmettin Erbakan University, Meram, Konya, Türkiye
,
Abdullah Yazar 
2   Department of Pediatrics, Meram Faculty of Medicine, Necmettin Erbakan University, Meram, Konya, Türkiye
,
Mehmet Özdemir
3   Department of Medical Microbiology, Meram Faculty of Medicine, Necmettin Erbakan University, Meram, Konya, Türkiye
,
Sevgi Pekcan 
1   Department of Pediatric Pulmonology, Meram Faculty of Medicine, Necmettin Erbakan University, Meram, Konya, Türkiye
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Abstract

This study aims to investigate and analyze the clinical features of coexisting human bocavirus (HBoV) positivity and plastic bronchitis (PB). We present three cases with no known history of cardiac surgery who presented with cough, progressive dyspnea, and atelectasis. They tested positive for HBoV in a real-time polymerase chain reaction of both nasal lavage fluids. They were diagnosed with PB as a result of bronchoscopy and pathology. PB is a rare disease characterized by forming thick rigid casts in the tracheobronchial tree, which can progress to respiratory failure. While asthma or atopy-related type 1 PB was observed in one patient, two patients were diagnosed with PB, which was thought to have developed secondary to viral infections of unknown etiology. As far as we know, HBoV-associated PB cases are rare in the literature. Besides the commonly known infectious agents, we identified a relationship with HBoV in all the presented cases.

Keywords

atelectasis - bronchiolitis - bronchoscopy - human bocavirus - plastic bronchitis

Consent to Participate and Consent to Publish

Patients gave written permission to participate and be published and share the images.


Ethical Approval

The patients gave written consent to participate and be published and share the images.


Availability of Data and Materials

Data and materials cannot be used without permission.




Publication History

Received: 31 December 2022

Accepted: 24 April 2023

Article published online:
26 May 2023

© 2023. Thieme. All rights reserved.

Georg Thieme Verlag KG
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