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CC BY 4.0 · Int Arch Otorhinolaryngol 2024; 28(03): e530-e536
DOI: 10.1055/s-0043-1769496
Systematic Review

Association between Benign Paroxysmal Positional Vertigo and Thyroid Diseases: Systematic Review and Meta-Analysis

Cyntia Machado Lima 
1   Postgraduate Program in Health Sciences, Faculty of Medicine, Universidade Federal da Bahia, Salvador, BA, Brazil
,
Daniel Felipe Fernandes Paiva 
2   Postgraduate Program in Odontology, Universidade de Campinas, Campinas, SP, Brazil
,
Ana Paula Corona 
3   Department of Speech-Language Pathology and Audiology, Universidade Federal da Bahia, Salvador, BA, Brazil
,
Marcus Miranda Lessa 
4   Department of Otorhinolaryngology, Universidade Federal da Bahia, Salvador, BA, Brazil
› Author Affiliations Funding Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 28001010072P3.
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Abstract

Introduction Benign paroxysmal positional vertigo (BPPV) is the peripheral vestibular dysfunction that most affects people worldwide, but its etiopathogenesis is still not fully understood. Considering the etiological diversity, some studies highlight the association between BPPV and thyroid diseases.

Objective To investigate the association between thyroid diseases and BPPV.

Data Synthesis Systematic review and meta-analysis of epidemiological studies searched in the PubMed, Web of Science, Embase, Cochrane Library, and Scopus databases. Studies that were fully available and investigated the association between BPPV and thyroid diseases were selected. The articles that composed the meta-analysis were analyzed using the dichotomous model, the Mantel-Haenszel statistical test, odds ratio (OR), and a 95% confidence interval (CI). Of the 67 articles retrieved from the databases, 7 met the eligibility criteria of the systematic review, and 4 had data necessary to perform the meta-analysis. Qualitative analysis revealed that the studies were conducted in the European and Asian continents. The predominant methodological design was the case-control type, and thyroid dysfunctions, hypothyroidism, and Hashimoto thyroiditis occurred more frequently. The meta-analysis showed no association between hypothyroidism and BPPV; however, there was a statistically significant relationship between Hashimoto thyroiditis and BPPV.

Conclusion The meta-analysis results suggest a possible association between BPPV and Hashimoto thyroiditis. Nevertheless, we emphasize the need for further studies to elucidate the evidence obtained.

Keywords

benign paroxysmal positional vertigo - hypothyroidism - hyperthyroidism - hashimoto thyroiditis

The present article is part of Cyntia Machado Lima's master's dissertation, presented on 04/01/2022




Publication History

Received: 06 January 2023

Accepted: 12 March 2023

Article published online:
14 September 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)

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