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DOI: 10.1055/s-0043-1770347
Nonalcoholic Wernicke encephalopathy with petechial hemorrhage in the tectal region
Encefalopatia de Wernicke não alcoólica com hemorragia petequial na região tectalA 39-year-old woman, after an episode of acute appendicitis, developed necrosis and intestinal obstruction, requiring colectomy and ileostomy. After hospital discharge, she had a high output through the ileostomy and low food intake. A few months later, she developed bilateral nystagmus, ataxic syndrome and difficulty concentrating. Susceptibility weighted imaging (SWI) sequence of the brain magnetic resonance imaging (MRI) showed hypointensities in the mammillary bodies and inferior colliculi, which might represent microbleeds ([Figure 1]).
Wernicke encephalopathy (WE) usually affects the mamillary bodies, thalami, and periaqueductal region. Rare hemorrhagic manifestations are reported in the literature, most in the mamillary bodies. The breakdown of the blood-brain barrier may contribute to this petechial hemorrhage in WE.[1] [2]
Authors' Contributions
All authors contributed equally to the present work.
Publication History
Received: 05 January 2023
Accepted: 25 February 2023
Article published online:
30 August 2023
© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)
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References
- 1 Zuccoli G, Santa Cruz D, Bertolini M. et al. MR imaging findings in 56 patients with Wernicke encephalopathy: nonalcoholics may differ from alcoholics. AJNR Am J Neuroradiol 2009; 30 (01) 171-176
- 2 Hattingen E, Beyle A, Müller A, Klockgether T, Kornblum C. Wernicke encephalopathy: SWI detects petechial hemorrhages in mammillary bodies in vivo. Neurology 2016; 87 (18) 1956-1957