Homeopathy
DOI: 10.1055/s-0043-1771023
Original Research Article

Homeopathic Medicines in the Management of Dermatophytosis (Tinea Infections): A Clinico-epidemiological Study with Pre–post Comparison Design

1   Department of AYUSH, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India
,
Danish Javed
1   Department of AYUSH, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India
,
Amit Srivastava
2   Regional Research Institute for Homeopathy, Imphal, Manipur, India
,
Renu Bala
3   Homeopathy Drug Research Institute, Lucknow, Uttar Pradesh, India
,
Nibha Giri
4   State Homeopathic Dispensary, Ghazipur, Uttar Pradesh, India
› Author Affiliations
Funding The study was not supported financially. The authors themselves provided the necessary funding for the project.

Abstract

Background Dermatophytosis is a common fungal infection of the skin and nails. Insufficient data exist regarding the clinico-epidemiological profile of dermatophytosis and the usefulness of individualized homeopathic medicines (IHMs) for patients visiting a homeopathy outpatient department (OPD).

Objectives This article undertakes a clinico-epidemiological profiling of dermatophytosis and the usefulness of IHMs in its management.

Methods This open-label, pre–post, comparative observational study was conducted in a homeopathy OPD from November 2018 to February 2020. IHMs were prescribed based on symptom totality and repertorization. A numeric rating scale (NRS) and the Dermatology Life Quality Index (DLQI) patient questionnaires were used, and results were analyzed using SPSS-IBM version 20.

Results Data from a total of 103 patients, mean age 29.65 ± 15.40 years, were analyzed. Tinea cruris was the most common infection (29.1%), followed by tinea corporis (13.6%). After 3 months of treatment, significant reductions in NRS and DLQI scores were observed (8.51 ± 1.24 to 0.59 ± 0.83, p < 0.001, and 16.28 ± 5.30 to 1.44 ± 1.56, p < 0.001, respectively), with Sepia (15.5%), Sulphur (14.6%), Calcarea carbonica (11.7%), Natrum muriaticum (9.7%) and Bacillinum (8.7%) being the most frequently prescribed medicines. There was no significant correlation between occupation, sex, home location or marital status and the clinical types of dermatophytosis. No adverse events were reported.

ConclusionT. cruris and T. corporis were prevalent dermatophytic infections. The decrease in NRS and DLQI scores associated with homeopathy indicates its usefulness as an integrative treatment option for dermatophytosis. Further research in larger and more diverse population samples is needed.

Authors' Contributions

A.K.D. conceptualized and developed the study and collected the data. The data were statistically analyzed and interpreted by A.K.D., A.S., and R.B.. The manuscript was prepared by A.K.D., D.J., and N.G. The final version was reviewed by all authors before being approved by each.


Supplementary Material



Publication History

Received: 24 March 2023

Accepted: 10 May 2023

Article published online:
01 November 2023

© 2023. Faculty of Homeopathy. This article is published by Thieme.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • References

  • 1 Fausi AS, Braunwald E, Kasper DL. et al. Harrison's Principle of Internal Medicine. 17th ed. New York: The McGraw Hill; 2008: 1264
  • 2 Poudyal Y, Joshi SD. Medication practice of patients with dermatophytosis. J Nepal Med Assoc 2016; 55: 7-10
  • 3 Havlickova B, Czaika VA, Friedrich M. Epidemiological trends in skin mycoses worldwide. Mycoses 2008; 51 (Suppl. 04) 2-15
  • 4 Bhagra S, Ganju SA, Kanga A, Sharma NL, Guleria RC. Mycological pattern of dermatophytosis in and around Shimla hills. Indian J Dermatol 2014; 59: 268-270
  • 5 Guruprasad KY, Javed MW, Roopa C, Ansari H, Takalkar AA. Clinico-epidemiological study of dermatophytosis in teaching hospital of North Karnataka. Int J Res Dermatol 2019; 5: 106-109
  • 6 Ho KM, Cheng TS. Common superficial fungal infections, a short review. Med Bull 2010; 15: 23-27
  • 7 Moriarty B, Hay R, Morris-Jones R. The diagnosis and management of tinea. BMJ 2012; 345: e4380
  • 8 Pandey A, Pandey M. Isolation and characterization of dermatophytes with tines infection at Gwalior (M.P.), India. Int J Pharm Sci Investig 2013; 2: 5-8
  • 9 Chakrabarti A, Sharma SC, Talwar P. Isolation of dermatophytes from clinically normal sites in patients with tinea cruris. Mycopathologia 1992; 120: 139-141
  • 10 Madhavi S, Rama Rao MV, Jyothsna K. Mycological study of dermatophytosis in rural population. Ann Biol Res 2011; 2: 88-93
  • 11 Venkatesan G, Singh AJA, Murugesan AG, Janaki C, Shankar SG. Trichophyton rubrum – the predominant aetiological agent in human dermatophytosis in Chennai, India. Afr J Microbiol Res 2007; 1: 9-12
  • 12 Grover S, Roy P. Clinico-mycological profile of superficial mycoses in hospital in North-East India. Med J Armed Forces India 2003; 59: 114-116
  • 13 Singh S, Beena PM. Profile of dermatophyte infections in Baroda. Indian J Dermatol Venereol Leprol 2003; 69: 281-283
  • 14 Reddy KN, Srikanth BA, Sharan TR, Biradar PM. Epidemiological, clinical and cultural study of onycomycosis. Am J Dermatol Venereol 2012; 1: 35-40
  • 15 Bhatia VK, Sharma PC. Epidemiological studies on dermatophytosis in human patients in Himachal Pradesh, India. Springerplus 2014; 3: 134
  • 16 Ely JW, Rosenfeld S, Stone MS. Diagnosis and management of tinea infections. Am Fam Physician 2014; 90: 702-710
  • 17 Dixit AK, Giri N. Tinea corporis: an evidence-based case report treated with homoeopathic medicine sepia. Homœopathic Links 2020; 33: 33-40
  • 18 Bala R, Srivastava A. Constitutional treatment of tinea cruris in homoeopathy – a case report. Int J Health Sci Res 2019; 9: 54-61
  • 19 Uttamchandani PA, Patil AD. Homoeopathy an alternative therapy for dermatophyte infections. Int J Health Sci Res 2019; 9: 316-320
  • 20 Simonart T, Kabagabo C, De Maertelaer V. Homoeopathic remedies in dermatology: a systematic review of controlled clinical trials. Br J Dermatol 2011; 165: 897-905
  • 21 National Ethical Guidelines for Biomedical Research Involving Children. . Accessed on December 17, 2022 at https://main.icmr.nic.in/sites/default/files/guidelines/National_Ethical_Guidelines_for_BioMedical_Research_Involving_Children_0.pdf
  • 22 Kent JT. Lectures on Homoeopathic Philosophy. Reprint Edition. New Delhi: B. Jain Publishers (P) Ltd.; 2006: 224-241
  • 23 Reich A, Chatzigeorkidis E, Zeidler C. et al. Tailoring the cut-off values of the visual analogue scale and numeric rating scale in itch assessment. Acta Derm Venereol 2017; 97: 759-760
  • 24 Basra MK, Fenech R, Gatt RM, Salek MS, Finlay AY. The Dermatology Life Quality Index 1994-2007: a comprehensive review of validation data and clinical results. Br J Dermatol 2008; 159: 997-1035
  • 25 Gupta S, Jain P. Role of homoeopathic medicines in tinea corporis: a case study. International Journal of Homoeopathic Sciences 2019; 3: 1-4
  • 26 Gupta Y, Tuteja S, Acharya A, Tripathi V. Effectiveness of homoeopathy in tinea corporis and tinea cruris – a prospective, longitudinal observational study. International Journal of Advanced Ayurveda, Yoga, Unani. Siddha and Homeopathy 2021; 10: 618-627
  • 27 Bhardwaj O, Manchanda R, Gupta R. Evaluation of Bacillinum in tinea infection. Br Homeopath J 1990; 79: 10-11
  • 28 Hazra P, Mukherjee SK, Ganguly S. et al. A comparative study of 50-millesimal potencies and centesimal potencies in the treatment of tinea corporis: an open, randomised, pilot trial. Homœopathic Links 2021; 34: 267-277
  • 29 Laskar B, Paul S, Chattopadhyay A. et al. Individualized homeopathic medicines in the treatment of tinea corporis: double-blind, randomized, placebo-controlled trial. Homeopathy 2023; 112: 74-84
  • 30 Sherr J, Davy J, Saghai Z, Quirk T, Fibert P. The comparative effectiveness of the homeopathic medicine Bacillinum for ringworm (tinea): a pilot feasibility study. Eur J Integr Med 2022; 53: 102142
  • 31 General Assembly of the World Medical Association. World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects. J Am Coll Dent 2014; 81: 14-18
  • 32 National Ethical Guidelines for Biomedical and Health Research Involving Human Participants. . Accessed December 17, 2022 at https://main.icmr.nic.in/sites/default/files/guidelines/ICMR_Ethical_Guidelines_2017.pdf