Synthesis, Table of Contents Synthesis 2025; 57(04): 876-882DOI: 10.1055/s-0043-1773506 paper Efficient Synthesis of the 6-Deoxy-l-talose-Containing Pentasaccharide Corresponding to the Cell Wall O-Polysaccharide of Escherichia coli O66 Puja Bag , Samim Sahaji , Anup Kumar Misra∗ Recommend Article Abstract Buy Article All articles of this category Abstract The pentasaccharide repeating unit containing 6-deoxy-l-talose corresponding to the cell wall O-polysaccharide of Escherichia coli (E. coli) O66 strain has been successfully synthesized in very good yield using sequential glycosylations of judiciously functionalized monosaccharide intermediates. Incorporation of the β-d-mannosidic linkage and 6-deoxy-α-l-talose in the pentasaccharide was achieved in excellent yield. Key words Key wordscarbohydrates - glycosylation - glycosides - oligosaccharides - synthesis Full Text References References 1a Podewils LJ, Mintz ED, Nataro JP, Parashar UD. Semin. Pediatr. Infect. 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