Squash Cytology Diagnosing Plasmacytoma of Frontal Bone as First Presentation of Nonsecretory Multiple Myeloma

Abstract

Plasmacytoma of bone is one of the criteria for diagnosing plasma cell myeloma (multiple myeloma). A plasmacytoma involving a frontal bone is unusual, with only few being reported so far. Also, when typical clinical presentation is absent, diagnosis is usually not suspected clinicoradiologically. We report a rare case of frontal bone plasmacytoma presenting as a lump over the forehead, the squash cytology of which gave the diagnosis of neoplastic etiology. Thus, squash cytology helped in early and definitive diagnosis in this patient, hastening meticulous diagnostic investigations and appropriate management. With full workup, the final diagnosis of a nonsecretory multiple myeloma was made.

Keywords

plasmacytoma - plasma cell neoplasm - myeloma - frontal bone - squash cytology

Author Contributions

Nagose VB has contributed in concept, design, definition of intellectual content, literature search, clinical studies, data acquisition, data analysis, manuscript preparation, editing, review and is acting as guarantor. Patil SB has contributed to concept, design, definition of intellectual content, clinical studies, data acquisition, manuscript editing and review. Mahajan NA has contributed to concept, clinical studies, data acquisition, manuscript editing and review.

Publication History

Article published online:
27 September 2023

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