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CC BY-NC-ND 4.0 · J Lab Physicians
DOI: 10.1055/s-0043-1774722
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Burkholderia vietnamiensis Causing Bacteremia in Patients Suffering from B-Cell Acute Lymphocytic Leukemia: A Case Series and Review of Literature

Mitra Kar 
1   Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
,
Akanksha Dubey 
1   Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
,
Chinmoy Sahu 
1   Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
,
Sangram Singh Patel 
1   Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
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Abstract

Burkholderia cepacia complex consists of 24 species of microorganisms that include B. cepacia, B. multivorans, B. cenocepacia, B. vietnamiensis, B. ambifaria, and many more. It is a ubiquitous microorganism found in the soil and aquatic milieu. The probability of infections in immunocompetent individuals is rare, but an increase in the population of immunocompromised patients in the past decade has attributed to increasing incidence of infections caused by these microorganisms. The most common infections caused by these isolates include bacteremia, pneumonia, genital tract infections, and surgical wound infections. Their potential to cause nosocomial outbreaks in wards of immunocompromised patients is well known. In this case series, we describe three cases of community-acquired Burkholderia vietnamiensis bacteremia in patients suffering from B-cell acute lymphocytic leukemia and their antibiotic sensitivity pattern to guide the treatment of these individuals.

Keywords

Burkholderia cepacia complex (BCC) - hematological malignancies - immunocompromised individuals - bacteremia - Burkholderia vietnamiensis

Authors' Contributions

Mitra Kar, Akanksha Dubey, and Sangram Singh Patel helped in protocol development. Akanksha Dubey and Mitra Kar helped in data collection. Chinmoy Sahu and Sangram Singh Patel helped in data analysis and supervision. Mitra Kar and Akanksha Dubey contributed to writing of the manuscript. Mitra Kar, Akanksha Dubey, Chinmoy Sahu, and Sangram Singh Patel reviewed and edited the manuscript. All authors read and approved the final version of the manuscript.




Publication History

Received: 26 December 2022

Accepted: 01 August 2023

Article published online:
03 October 2023

© 2023. The Indian Association of Laboratory Physicians. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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