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Synthesis 2024; 56(16): 2558-2564
DOI: 10.1055/s-0043-1774866
DOI: 10.1055/s-0043-1774866
paper
Radical Allylation of Aldehydes with Allenes by Photoredox Cobalt and Chromium Dual Catalysis
The project was supported by the National Natural Science Foundation of China (22171036), the Natural Science Foundation of Henan Province (232300421126), and the Open Research Fund of School of Chemistry and Chemical Engineering, Henan Normal University (2020YB03).
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Abstract
A dual cobalt and chromium photoredox-catalyzed allylation of aldehydes with allenes through a photo metal-hydride atom transfer (MHAT) process has been developed to yield homoallylic alcohols with exceptional diastereoselective control. This sustainable and efficient method holds significant promise for applications in the synthesis of valuable organic compounds.
Key words
photocatalysis - metal-hydride atom transfer (MHAT) - allenes - allylation - cobalt - homoallylic alcoholsSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0043-1774866.
- Supporting Information
Publication History
Received: 31 March 2024
Accepted after revision: 01 May 2024
Article published online:
23 May 2024
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