Synthesis 2024; 56(16): 2529-2536
DOI: 10.1055/s-0043-1775369
paper

Metal-Free Synthesis of Selanyl-Substituted Chromenones via Selanylation­/Cyclization of Alkynyl Aryl Ketones

Xi-Rui Gong
,
Yi-Huan Zhou
,
Mei-Lin Ren
,
Yan-Yan Chen
,
Yan-Li Xu
We would like to thank the National Natural Science Foundation of China (21861015), Guangxi Funds for Distinguished Experts, The Youth Promotion Fund of Guangxi (2024KY0527) and the Cultivation Plan of Thousands of Young and Middle-aged Backbone Teachers in Guangxi Colleges and Universities.


Abstract

A variety of 2-substituted 3-selanyl-chromenones are readily prepared through a cascade selanylation/cyclization of alkynyl aryl ketones with sulfonoselenoates. This transformation is performed under metal-free conditions and does not require an additional oxidant. It also has the advantage of broad functional group tolerance and scalability.

Supporting Information



Publication History

Received: 26 March 2024

Accepted after revision: 21 May 2024

Article published online:
12 June 2024

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