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CC BY-NC-ND 4.0 · Ann Natl Acad Med Sci 2023; 59(04): 175-185
DOI: 10.1055/s-0043-1775599
Review Article

A Comprehensive Review on Applicability and Bioactivity of Rogan-I-Kunjad (Sesamum indicum L-Oil): Unani Prospective

Saima Naseem
1   Department of Medicine, National Research Institute of Unani Medicine for Skin Disorders, Erragudda, Hyderabad, Telangana, India
,
Asif Ahmad Khan 
1   Department of Medicine, National Research Institute of Unani Medicine for Skin Disorders, Erragudda, Hyderabad, Telangana, India
,
Qamar Uddin
1   Department of Medicine, National Research Institute of Unani Medicine for Skin Disorders, Erragudda, Hyderabad, Telangana, India
,
Arzeena Jabeen
1   Department of Medicine, National Research Institute of Unani Medicine for Skin Disorders, Erragudda, Hyderabad, Telangana, India
,
Kamal Ahmad
1   Department of Medicine, National Research Institute of Unani Medicine for Skin Disorders, Erragudda, Hyderabad, Telangana, India
,
Mohd Asad
1   Department of Medicine, National Research Institute of Unani Medicine for Skin Disorders, Erragudda, Hyderabad, Telangana, India
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Abstract

Sesame oil has a long history of usage as a food and medicine. It is the most used oil as a medicine or as a base oil for preparations of many compound drugs in the Unani system of medicine. It has a wide range of biological activities as mentioned in Unani classical text; this review highlights its pharmacological activities and their possible mode of action. Searched many Unani classical literature online and offline and simultaneously did parallel search on databases like PubMed, and Science Direct, and extraction of data related to sesame oil, sesame seeds with its pharmacological activities, mode of action, then interpretation and summarization of all related data. Sesame oil possesses many biological activities like anti-inflammatory, antihyperlipidemic, antiatherosclerotic, hepatoprotective, antiasthmatic, analgesic, emollient, antipruritic, and wound healing effects, which were scientifically demonstrated as mentioned in Unani literature. Sesame oil has a hopeful effect on modulating diseases with no significant toxic effect; so, there is a need to identify its safety and efficacy on human subjects to develop a new potential drug.

Keywords

pharmacology - Rogan-I-Kunjad - sesame oil - Sesamum indicum L. - Unani medicine


Publication History

Article published online:
21 December 2023

© 2023. National Academy of Medical Sciences (India). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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