Sporadic Mesenteric Fibromatosis with Colonic Entrapment Mimicking Gastrointestinal Stromal Tumor—A Rare Entity: Two Case Reports

Mesenteric fibromatosis (MF), also known as desmoid tumors of the mesentery, is rare, locally aggressive fibroblastic proliferation of mesentery that tends to recur locally without distant metastasis. The clinical behavior of desmoids is unpredictable varying from indolent to aggressive. Radiologically, mesenteric fibromatosis could have infiltrative margin or well-defined, lobulated margin at presentation. The commonest site of mesenteric fibromatosis is small bowel mesentery.

Though the diagnosis of MF with infiltrative margins is rather easy, mesenteric fibromatosis with well-defined margins can be confused radiologically with gastrointestinal stromal tumor (GIST).[1] [2] Histopathology confirmation is essential for a definitive diagnosis.

We, herein, present two cases with well-defined margins mimicking GIST arising from small bowel mesentery with entrapped segment of colonic loop within the lesion.

Publication History

Article published online:
12 October 2023

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