Molecular Mimicry between Meningococcal B Factor H-Binding Protein and Human Proteins

Darja Kanduc

doi:10.1055/s-0043-1776985

Global Medical Genetics, Table of Contents

CC BY 4.0 · Glob Med Genet 2023; 10(04): 311-314
DOI: 10.1055/s-0043-1776985

Original Article

Molecular Mimicry between Meningococcal B Factor H-Binding Protein and Human Proteins

Darja Kanduc

¹Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari, Italy

› Author Affiliations

Abstract

This study calls attention on molecular mimicry and the consequent autoimmune cross reactivity as the molecular mechanism that can cause adverse events following meningococcal B vaccination and warns against active immunizations based on entire antigen.

Keywords

molecular mimicry - Trumenba vaccine - factor H-binding protein - human proteome - adverse events

Full Text

References

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Supplementary Material

Supplementary Material