Sjogren's syndrome: a neurological perspective

Orlando Grazianni Povoas Barsottini; Marianna Pinheiro Moraes de Moraes; Pedro Henrique Almeida Fraiman; Victor Hugo Rocha Marussi; Alexandre Wagner Silva de Souza; Pedro Braga Neto; Mariana Spitz

doi:10.1055/s-0043-1777105

Arquivos de Neuro-Psiquiatria, Table of Contents

CC BY 4.0 · Arq Neuropsiquiatr 2023; 81(12): 1077-1083
DOI: 10.1055/s-0043-1777105

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Sjogren's syndrome: a neurological perspective

Síndrome de Sjogren: uma perspectiva neurológica

Orlando Grazianni Povoas Barsottini

¹Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Neurologia e Neurocirurgia, Setor de Neurologia Geral e Ataxias, São Paulo SP, Brazil.

,

Marianna Pinheiro Moraes de Moraes

¹Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Neurologia e Neurocirurgia, Setor de Neurologia Geral e Ataxias, São Paulo SP, Brazil.

,

Pedro Henrique Almeida Fraiman

¹Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Neurologia e Neurocirurgia, Setor de Neurologia Geral e Ataxias, São Paulo SP, Brazil.

,

Victor Hugo Rocha Marussi

²Hospital Beneficência Portuguesa, Setor de Neurorradiologia, São Paulo SP, Brazil.

,

Alexandre Wagner Silva de Souza

³Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Medicina, Divisão de Reumatologia, São Paulo SP, Brazil.

⁴Sociedade Brasileira de Reumatologia, Comissão de Vasculites, São Paulo SP, Brazil.

,

Pedro Braga Neto

⁵Universidade Federal do Ceará, Departamento de Medicina Clínica, Divisão de Neurologia, Fortaleza CE, Brazil.

⁶Universidade do Estado do Ceará, Centro de Ciências da Saúde, Fortaleza CE, Brazil.

,

Mariana Spitz

⁷Universidade do Estado do Rio de Janeiro, Serviço de Neurologia, Rio de Janeiro RJ, Brazil.

› Author Affiliations

Abstract

Sjogren's syndrome (SS) is a complex autoimmune disease characterized by lymphocytic infiltration of salivary and lacrimal glands, resulting in sicca symptoms. Additionally, SS presents with neurological manifestations that significantly impact the nervous system. This review aims to provide a comprehensive overview of the neurological aspects of SSj, covering both the peripheral and central nervous system involvement, while emphasizing diagnosis, treatment, and prognosis.

Resumo

A síndrome de Sjogren (SS) é uma doença autoimune complexa caracterizada pela infiltração linfocítica das glândulas salivares e lacrimais, resultando em sintomas sicca. Além disso, a SS apresenta manifestações neurológicas que afetam significativamente o sistema nervoso. Esta revisão tem como objetivo fornecer uma visão abrangente dos aspectos neurológicos da SSj, abordando tanto o envolvimento do sistema nervoso periférico quanto do central, com ênfase no diagnóstico, tratamento e prognóstico.

Keywords

Sjogren's Syndrome - Autoimmune Diseases of the Nervous System

Palavras-chave

Síndrome de Sjogren - Doenças Autoimunes do Sistema Nervoso

Full Text

References

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