Facial Plast Surg 2024; 40(02): 129-145
DOI: 10.1055/s-0043-1777311
Original Article

Paradigm Shift from Linear Strip to Follicular Unit Excision in Hair Restoration Surgery

1   Department of Surgical Hair Restoration, Anastasakis Hair Clinic, Athens, Attiki, Greece
› Author Affiliations

Abstract

Follicular unit excision (FUE) is a very effective and valuable modality for obtaining donor hair follicles using manual, motorized, or robotic devices to harvest individual donor follicular units in situ without a linear donor scar or visible scarring making it ideal for patients who wish to wear their hair short and hide signs of surgery. Over the past two decades, FUE has become increasingly popular, and the rising demand for FUE has driven the worldwide market size of hair restoration surgery (HRS) to an unprecedented height.

FUE has revolutionized the HRS industry and offers excellent cosmesis and high patient satisfaction. Unfortunately, a large part of the favorable appeal of FUE is due to false claims that it is “minimally invasive,” “scarless,” or “not even surgery.” Most patients opt-in for FUE due to these misconceptions, which are advertised by “black-market” clinics offering low-cost FUE surgery performed by amateur, nonprofessional technicians on unsuspected patients. The technique appears deceptively simple, and many neophyte surgeons falsely believe that the learning curve of FUE is short because the barrier of entry is low and no previous surgical skill is required. Nevertheless, injuries on grafts are extremely easy to occur since FUE is a blind technique and can be minimized only with excellent technique, which takes years to master.

FUE actually presents unique challenges for the surgeon and carries potential long-term permanent side effects if not performed properly. The surgeon must have a thorough understanding of the nuances of the FUE surgical technique to ensure consistent graft quality and favorable cosmesis of both donor and recipient areas. Efficient FUE requires dexterity, training, dedication, devotion, enthusiasm, cognitive clarity, scientific knowledge, experience, and an extended learning curve.

FUE is an invaluable addition to the armamentarium of a hair restoration surgeon but has to be judiciously performed.



Publication History

Article published online:
13 December 2023

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  • References

  • 1 Pierce HE. The strip graft as a means of hairline replacement. J Natl Med Assoc 1977; 69 (07) 509-510
  • 2 Bernstein RM, Rassman WR, Seager D. et al. Standardizing the classification and description of follicular unit transplantation and mini-micrografting techniques. The American Society for Dermatologic Surgery, Inc. Dermatol Surg 1998; 24 (09) 957-963
  • 3 Stough III DB, Mendoza F, Freilich IW. Surgical procedures for the treatment of baldness. Cutis 1986; 37 (05) 362-365
  • 4 Limmer BL. Elliptical donor stereoscopically assisted micrografting as an approach to further refinement in hair transplantation. J Dermatol Surg Oncol 1994; 20 (12) 789-793
  • 5 Bernstein RM, Rassman WR, Szaniawski W. Follicular transplantation. Int J Aesthet Restor Surg. 1995; 3: 119-132
  • 6 Headington JT. Transverse microscopic anatomy of the human scalp. A basis for a morphometric approach to disorders of the hair follicle. Arch Dermatol 1984; 120 (04) 449-456
  • 7 Bernstein RM, Rassman WR. The logic of follicular unit transplantation. Dermatol Clin 1999; 17 (02) 277-295 , viii, discussion 296
  • 8 Bernstein RM, Rassman WR. The aesthetics of follicular transplantation. Dermatol Surg 1997; 23 (09) 785-799
  • 9 Rassman WR, Bernstein RM, McClellan R, Jones R, Worton E, Uyttendaele H. Follicular unit extraction: minimally invasive surgery for hair transplantation. Dermatol Surg 2002; 28 (08) 720-728
  • 10 Inaba M. Androgenetic alopecia: modern concepts in pathogenesis and treatment. Tokyo: Springer; 1996: 238-245
  • 11 Rassman WR, Pak J, Kim J. Follicular unit extraction: evolution of a technology. J Transplant Technol Res 2016; 6: 158
  • 12 Kim YS, Na YC, Park JH. Comparison of postoperative pain according to the harvesting method used in hair restorative surgery. Arch Plast Surg 2019; 46 (03) 241-247
  • 13 Garg S, Garg AK. Study of ropivacaine block to reduce post-operative pain after strip harvesting, and the relationship of strip width to post-operative pain. Hair Transplant Forum Int 2019; 29 (05) 186-188
  • 14 Harris JA. New methodology and instrumentation for follicular unit extraction: lower follicle transection rates and expanded patient candidacy. Dermatol Surg 2006; 32 (01) 56-61 , discussion 61–62
  • 15 Habif T. Clinical Dermatology. 5th ed.. Amsterdam: Elsevier; 2015
  • 16 Harris JA. Follicular unit extraction. Facial Plast Surg 2008; 24 (04) 404-413
  • 17 Umar S. Use of beard hair as a donor source to camouflage the linear scars of follicular unit hair transplant. J Plast Reconstr Aesthet Surg 2012; 65 (09) 1279-1280
  • 18 Wu WY, Otberg N, Kang H, Zanet L, Shapiro J. Successful treatment of temporal triangular alopecia by hair restoration surgery using follicular unit transplantation. Dermatol Surg 2009; 35 (08) 1307-1310
  • 19 Garg AK, Garg S. Donor harvesting: follicular unit excision. J Cutan Aesthet Surg 2018; 11 (04) 195-201
  • 20 Bernstein RM, Rassman WR. New instrumentation for 3-step follicular unit extraction. Hair Transplant Forum Int 2006; 16 (01) 229
  • 21 Cole JP. An analysis of follicular punches, mechanics, and dynamics in follicular unit extraction. Facial Plast Surg Clin North Am 2013; 21 (03) 437-447
  • 22 Mohebi P, Straga J. Dynamics of FUE. Hair Transplant Forum Int 2017; 27 (06) 232-236
  • 23 Anastassakis K. Follicular unit excision (FUE). In: Androgenetic Alopecia from A to Z. Cham: Springer; 2023. . Accessed 11 November 2023 at https://doi.org/10.1007/978-3-031-10613-2_10
  • 24 Lam SM, Williams K. Hair Transplant 360: Follicular Unit Extraction (FUE). 1st ed.. New Delhi: Jaypee Brothers Medical Publishers; 2016: 252
  • 25 Harris JA. The SAFE SystemR: new instrumentation and methodology to improve follicular unit extraction (FUE). Hair Transplant Forum Int 2004; 14 (05) 157
  • 26 Mohebi P, Lorenzo J, Devroye JM. et al. FUE Research Committee Chair's Message: standardization of the terminology used in FUE: part I. Hair Transplant Forum Int 2013; 23 (05) 165-168
  • 27 Epstein GK, Epstein J, Nikolic J. Follicular unit excision: current practice and future developments. Facial Plast Surg Clin North Am 2020; 28 (02) 169-176
  • 28 True R. et al. A 2019 guide to currently accepted FUE and implanter terminology. Hair Transplant Forum Int 2019; 29 (03) 98-106
  • 29 Unger W. Commentary. Dermatol Surg 2002; 28 (08) 720-728
  • 30 Zontos G, Rose PT, Nikiforidis G. A mathematical proof of how the outgrowth angle of hair follicles influences the injury to the donor area in FUE harvesting. Dermatol Surg 2014; 40 (10) 1147-1150
  • 31 Park JH, You SH. Various types of minor trauma to hair follicles during follicular unit extraction for hair transplantation. Plast Reconstr Surg Glob Open 2017; 5 (03) e1260
  • 32 Karaçal N, Uraloğlu M, Dindar T, Livaoğlu M. Necrosis of the donor site after hair restoration with follicular unit extraction (FUE): a case report. J Plast Reconstr Aesthet Surg 2012; 65 (04) e87-e89
  • 33 Vogel JE. Hair restoration complications: an approach to the unnatural-appearing hair transplant. Facial Plast Surg 2008; 24 (04) 453-461
  • 34 Yoo H, Moh J, Park JU. Treatment of postsurgical scalp scar deformity using follicular unit hair transplantation. BioMed Res Int 2019; 2019: 3423657
  • 35 Crisostomo MR. et al. Untouched strip: a technique to increase the number of follicular units in hair transplants while preserving an untouched area for future surgery. Surg Cosmet Dermatol 2011; 3 (04) 361-364
  • 36 Mohebi P, Carman T. How I do it: serial extraction–placement FUE technique. Hair Transplant Forum Int 2016; 26 (03) 104-105
  • 37 Josephitis D, Shapiro R. A side-by-side study of FUT vs. FUE graft availability in the same patients and its implications on lifetime donor supply and management. Hair Transplant Forum Int 2019; 29 (05) 177-185
  • 38 Beehner ML. A comparison of hair growth between follicular-unit grafts trimmed “skinny” vs. “chubby”. Dermatol Surg 1999; 25 (04) 339-340
  • 39 Ors S, Ozkose M, Ors S. Follicular unit extraction hair transplantation with micromotor: eight year's experience. Aesthet Plast Surg 2015; 39 (04) 589-596
  • 40 ISHRS Follicular Unit Excision Advancement Committee (FUEAC). FUE clinical practice guidelines. Hair Transplant Forum Int 2019; 29 (04) 139-150
  • 41 Bernstein RM. Controversies: FUE and donor depletion: age and the donor zone in FU hair transplants. Hair Transplant Forum Int 2013; 23 (03) 86-93
  • 42 Haber R. FUT fights back. Hair Transplant Forum Int 2015; 25 (05) 177-187
  • 43 Knudsen R. Controversies: the temporary hair transplant: a novel idea or making a virtue out of necessity?. Hair Transplant Forum Int 2018; 28 (02) 6
  • 44 Knudsen R. Notes from the Editor Emeritus: the temporary two-thirds transplant?. Hair Transplant Forum Int 2014; 24 (05) 165
  • 45 Bernstein RM. Commentary on robotic follicular unit extraction in hair transplantation. Dermatol Surg 2015; 41 (02) 279
  • 46 Harris JA. The Development and Application of the Hair Diameter Index (HDI). Hair Transplant Forum Int 2021; 31 (01) 1-8
  • 47 Keene SA, Rassman WR, Harris JA. Determining safe excision limits in FUE: factors that affect, and a simple way to maintain, aesthetic donor density. Hair Transplant Forum Int 2018; 28 (01) 1-11
  • 48 Mohmand MH, Ahmad M. Transection rate at different areas of scalp during follicular unit extraction/excision (FUE). J Cosmet Dermatol 2020; 19 (07) 1705-1708
  • 49 True R. Notes from the Editor Emeritus, 2014–2016: my journey in the evolution of FUE. Hair Transplant Forum Int 2019; 29 (01) 7-9
  • 50 Lam SM, Williams KW. Hair Transplant 360, Volume 4: Follicular Unit Excision. 2nd ed.. New Delhi: Jaypee Brother Medical Publishers; 2021
  • 51 Knudsen RG. Notes from the Editor Emeritus: ethics and follicular unit extraction. Hair Transplant Forum Int 2016; 26 (04) 133
  • 52 Huang YL, Lee MC, Chang SL. et al. Harvested vs estimated follicular units in hair transplantation. J Cosmet Dermatol 2019; 18 (03) 902-907
  • 53 Williams G. Medical and professional ethics: spotlight on surgery by unlicensed practitioners. Hair Transplant Forum Int 2018; 28 (05) 192-193
  • 54 Knudsen R. Controversies: what should the ISHRS do about non-physicians performing hair transplantations?. Hair Transplant Forum Int 2012; 22 (03) 83
  • 55 Rassman WR. The future of hair transplantation. Hair Transplant Forum Int 2015; 25 (05) 198-199
  • 56 Keene SA. et al. Response to Dr. Rassman's opinion on the future of hair restoration surgery. Hair Transplant Forum Int 2015; 25 (06) 264-265