Download PDF
CC BY-NC-ND 4.0 · Indian J Plast Surg 2000; 33(02): 086-089
DOI: 10.1055/s-0043-1778539
Review Article

Effect of Topical Atropine on Wound Contraction in Swiss Albino Mice : A preliminary report

P Kumar
1   Department of Plastic Surgery, Kastruba Medical College, Manipal 576 119, Kamataka, India
,
G C Jagetia
2   Department of Radiobiology, Kastruba Medical College, Manipal 576 119, Kamataka, India
› Author Affiliations
› Further Information
Also available at
  PDF Download Permissions and Reprints

SUMMARY

The influence of topical application of atropine ointment was studied in artificially wounded Swiss albino mice. Full thickness excision wounds were made surgically on the dorsum of mice. One mm thick layer of atropine ointment was applied topically on the whole area of wound daily, till the healing of wound. The topical application of atropine ointment significantly delayed the contraction of wound in the atropine treated group when compared with the untreated controls. There was a significant delay in the mean wound healing time (HTM) in the atropine treated group when compared to untreated control group.



Publication History

Article published online:
06 March 2024

© 2024. Association of Plastic Surgeons of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India