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CC BY 4.0 · World J Nucl Med
DOI: 10.1055/s-0044-1778708
Case Report

Flourine-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Imaging of Peritoneal Carcinomatosis in Lung Cancer: A Case Study

Tshimogo Sathekge
1   Faculty of Health Science, University of Witwatersrand, Johannesburg, South Africa
,
Raef R. Boktor
2   Department of Molecular Imaging and Therapy, Austin Health, Melbourne, VIC, Australia
3   Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia
4   School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia
,
Salvatore Berlangieri
2   Department of Molecular Imaging and Therapy, Austin Health, Melbourne, VIC, Australia
,
Sze Ting Lee
2   Department of Molecular Imaging and Therapy, Austin Health, Melbourne, VIC, Australia
3   Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia
4   School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia
5   Faculty of Medicine, University of Melbourne, Melbourne, VIC, Australia
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Abstract

Lung cancer with peritoneal carcinomatosis (PC) is a rare disease presentation. The presence of peritoneal disease is a sign of poor prognosis and is hard to diagnose. Flourine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) is becoming more clinically significant in the management of patients with PC. A 60-year-old male presented with nonsmall cell lung cancer (NSCLC) and later showed signs of peritoneal disease on 18F-FDG PET/CT imaging, which subsequently lead to the diagnoses of PC with histopathology from peritoneal biopsy. The patient showed an excellent initial response to their NSCLC treatment but later presented with PC that was shown by FDG-avid ascites and a soft tissue mass in the pelvic area. The abdominal-pelvic lesions were confirmed cytologically to be peritoneal metastatic disease. 18F-FDG PET/CT demonstrated value in preoperatively directing biopsy for diagnosing PC in this case of NSCLC. Further, 18F-FDG PET/CT was useful in the monitoring of disease progression and thus influenced management in this case of NSCLC with PC, which is often challenging to detect and manage.

Keywords

18F-FDG PET/CT - peritoneal carcinomatosis - lung cancer - NSCLC - peritoneal biopsy


Publication History

Article published online:
27 June 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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