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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2024; 34(03): 441-448
DOI: 10.1055/s-0044-1779303
Original Article

Impact of the Timing of Percutaneous Catheter Drainage following Endoscopic Drainage on Outcomes in Acute Necrotizing Pancreatitis

Harsimran Bhatia
1   Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Sanya Vermani
1   Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Pankaj Gupta 
1   Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Shameema Farook
1   Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Abhishek Kumar
1   Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Joseph Johnson
1   Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Jimil Shah
2   Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Anupam Singh
2   Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Vaneet Jearth
2   Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Jayanta Samanta 
2   Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Harshal Mandavdhare
2   Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Vishal Sharma 
2   Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Saroj K. Sinha
2   Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Usha Dutta
2   Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Rakesh Kocchar
2   Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
› Author Affiliations Funding None.
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Abstract

Background The role of dual-modality drainage of walled-off necrosis (WON) in patients with acute pancreatitis (AP) is established. However, there are no data on the association of clinical outcomes with the timing of percutaneous catheter drainage (PCD). We investigated the impact of the timing of PCD following endoscopic drainage of WON on clinical outcomes in AP.

Materials and Methods This retrospective study comprised consecutive patients with necrotizing AP who underwent endoscopic cystogastrostomy (CG) of WON followed by PCD between September 2018 and March 2023. Based on endoscopic CG to PCD interval, patients were divided into groups (≤ and >3 days, ≤ and >1 week, ≤ and >10 days, and ≤ and >2 weeks). Baseline characteristics and indications of CG and PCD were recorded. Clinical outcomes were compared between the groups, including length of hospitalization, length of intensive care unit stay, need for surgical necrosectomy, and death during hospitalization.

Results Thirty patients (mean age ± standard deviation, 35.5 ± 12.7 years) were evaluated. The mean CG to PCD interval was 11.2 ± 7.5 days. There were no significant differences in baseline characteristics and indications of CG and PCD between the groups. The mean pain to CG interval was not significantly different between the groups. Endoscopic necrosectomy was performed in a significantly greater proportion of patients undergoing CG after 10 days (p = 0.003) and after 2 weeks (p = 0.032). There were no significant differences in the complications and clinical outcomes between the groups.

Conclusion The timing of PCD following endoscopic CG does not affect clinical outcomes.

Keywords

acute pancreatitis - collections - drainage - endoscopy - catheter

Ethical Approval and Patient Consent

The institute ethics committee approved the study and waived the consent to obtain consent due to its retrospective nature.


Authors' Contributions

H.B., S.V., P.G., S.F., A.K., and J.J. contributed to data acquisition, analysis, initial draft, revision, and final approval. J.S., A.S., V.J., H.M., J.S., V.S., S.K.S., U.D., and R.K. contributed to data acquisition, revision, and final approval.




Publication History

Article published online:
31 January 2024

© 2024. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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